Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in
the central nervous system. MS is characterized by its most common symptoms of spasticity …

The objective was to determine whether a cannabis-based medicinal extract (CBME)
benefits a range of symptoms due to multiple sclerosis (MS). A parallel group, double-blind …

Symptoms relating to spasticity are common in multiple sclerosis (MS) and can be difficult to
treat. We have investigated the efficacy, safety and tolerability of a standardized oromucosal …

Objective: Debilitating pain, occurring in 50–70% of multiple sclerosis (MS) patients, is
poorly understood and infrequently studied. We summarized efficacy and safety data of …

Importance Cannabinoids have antispastic and analgesic effects; however, their role in the
treatment of multiple sclerosis (MS) symptoms is not well defined. Objective To conduct a …

The object of this study was to monitor the safety and efficacy of long-term use of an
oromucosal cannabis-based medicine (CBM) in patients with multiple sclerosis (MS). A total …

Abstract Purpose of Review Cannabis and cannabinoids have been used medically and
recreationally for thousands of years and recently there has been a growing body of …

Background: Central pain in multiple sclerosis (MS) is common and often refractory to
treatment. Methods: We conducted a single-center, 5-week (1-week run-in, 4-week …

Abstract Purpose of Review Pharmaceutical cannabinoids such as nabiximols, nabilone and
dronabinol, and plant-based cannabinoids have been investigated for their therapeutic …

Introduction Patients with multiple sclerosis (MS) may suffer from spasticity and pain during
their disease course. Baclofen, dantrolene, diazepam and gabapentin have been used as …