Hepatocellular carcinoma (HCC) and diagnostic significance of A-fetoprotein (AFP).
JA Baig, JM Alam, SR Mahmood, M Baig… - Journal of Ayub …, 2009 - europepmc.org
Background Alpha-fetoprotein (alpha-fetoprotein, AFP) is a Glycoprotein, belonging to the
intriguing class of onco-development protein. Generally designated as tumour marker, AFP …
intriguing class of onco-development protein. Generally designated as tumour marker, AFP …
[HTML][HTML] Persistently rising alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: a review
A Turshudzhyan, GY Wu - Journal of Clinical and Translational …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), one of the most common malignant tumors worldwide, is
known for its grim prognosis, with untreated life expectancy being only a matter of months …
known for its grim prognosis, with untreated life expectancy being only a matter of months …
Alpha-fetoprotein enhances the proliferation of human hepatoma cells in vitro
XW Wang, H Xie - Life sciences, 1998 - Elsevier
Although the biological functions of alpha-fetoprotein (AFP) have been extensively studied,
little is known about its effect on tumor cell growth. Our previous work has found that human …
little is known about its effect on tumor cell growth. Our previous work has found that human …
Diagnosing and monitoring hepatocellular carcinoma with alpha-fetoprotein: new aspects and applications
EN Debruyne, JR Delanghe - Clinica chimica acta, 2008 - Elsevier
Hepatocellular carcinoma is the 5th most common cancer in the world. Prognosis for this
disease is poor since hepatocellular carcinoma is mostly diagnosed at an advanced stage …
disease is poor since hepatocellular carcinoma is mostly diagnosed at an advanced stage …
Current status and perspective biomarkers in AFP negative HCC: towards screening for and diagnosing hepatocellular carcinoma at an earlier stage
P Luo, S Wu, Y Yu, X Ming, S Li, X Zuo, J Tu - Pathology & Oncology …, 2020 - Springer
Hepatocellular carcinoma (HCC) is one of the most malignant cancer with high morbidity
and mortality which lead to a serious burden to society. AFP (alpha-fetoprotein) is the most …
and mortality which lead to a serious burden to society. AFP (alpha-fetoprotein) is the most …
Alpha fetoprotein promotes polarization of macrophages towards M2-like phenotype and inhibits macrophages to phagocytize hepatoma cells
M Zhang, K Liu, Q Zhang, J Xu, J Liu, H Lin… - Frontiers in …, 2023 - frontiersin.org
Alpha-fetoprotein (AFP) is a cancer biomarker for the diagnosis of hepatocellular carcinoma
(HCC); however, its role in macrophage polarization and phagocytosis remains unclear. In …
(HCC); however, its role in macrophage polarization and phagocytosis remains unclear. In …
Alpha-fetoprotein for diagnosis, prognosis, and transplant selection
F Trevisani, F Garuti, A Neri - Seminars in Liver Disease, 2019 - thieme-connect.com
Reliable biomarkers are of great clinical value in predicting cancer occurrence/recurrence,
anticipating its detection at an asymptomatic stage, supporting the radiological diagnosis …
anticipating its detection at an asymptomatic stage, supporting the radiological diagnosis …
Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of Lens culinaris agglutinin‐reactive α‐fetoprotein1
H Oka, A Saito, K Ito, T Kumada… - Journal of …, 2001 - Wiley Online Library
Abstract Background and Aim: The Lens culinaris agglutinin‐reactive fraction of α‐
fetoprotein (AFP‐L3) has been reported to be a highly useful marker for hepatocellular …
fetoprotein (AFP‐L3) has been reported to be a highly useful marker for hepatocellular …
Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials
R Montal, C Andreu-Oller, L Bassaganyas… - British journal of …, 2019 - nature.com
The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma
(HCC) is widely recognised. However, a clear understanding of the mechanisms of AFP …
(HCC) is widely recognised. However, a clear understanding of the mechanisms of AFP …
Prognostic role of pre-treatment serum AFP-L3% in hepatocellular carcinoma: systematic review and meta-analysis
J Cheng, W Wang, Y Zhang, X Liu, M Li, Z Wu, Z Liu… - PloS one, 2014 - journals.plos.org
Background Serum lens culinaris agglutinin-reactive fraction of α-fetoprotein (AFP-L3%) has
been widely used for HCC diagnosis and follow-up surveillance as tumor serologic marker …
been widely used for HCC diagnosis and follow-up surveillance as tumor serologic marker …