Viruses can silently prime for and trigger central nervous system autoimmune disease
DJ Theil, I Tsunoda, F Rodriguez, JL Whitton… - Journal of …, 2001 - Springer
Although many viruses have been isolated from patients with multiple sclerosis (MS), as yet,
no one agent has been demonstrated to cause MS. In contrast, epidemiological data …
no one agent has been demonstrated to cause MS. In contrast, epidemiological data …
CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge
CM Matullo, KJ O'Regan, M Curtis, GF Rall - PLoS Pathogens, 2011 - journals.plos.org
Although viruses have been implicated in central nervous system (CNS) diseases of
unknown etiology, including multiple sclerosis and amyotrophic lateral sclerosis, the …
unknown etiology, including multiple sclerosis and amyotrophic lateral sclerosis, the …
Viruses and multiple sclerosis
GP Owens, D Gilden, MP Burgoon, X Yu… - The …, 2011 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic demyelinating disorder of unknown etiology, possibly
caused by a virus or virus-triggered immunopathology. The virus might reactivate after years …
caused by a virus or virus-triggered immunopathology. The virus might reactivate after years …
Neural immunity: Friend or foe?
HE Gendelman - Journal of neurovirology, 2002 - Taylor & Francis
The articles compiled in this special edition of Journal of NeuroVirology target a developing
field of investigation seeking to uncover how the immune system affects both the pathogenic …
field of investigation seeking to uncover how the immune system affects both the pathogenic …
Multiple sclerosis and virus induced immune responses: autoimmunity can be primed by molecular mimicry and augmented by bystander activation
L McCoy, I Tsunoda, RS Fujinami - Autoimmunity, 2006 - Taylor & Francis
Polymicrobial infections have been associated with plausible immune mediated diseases,
including multiple sclerosis (MS). Virus infection can prime autoimmune T cells specific for …
including multiple sclerosis (MS). Virus infection can prime autoimmune T cells specific for …
[HTML][HTML] Viral triggers of multiple sclerosis
K Kakalacheva, C Münz, JD Lünemann - Biochimica et Biophysica Acta …, 2011 - Elsevier
Genetic and environmental factors jointly determine the susceptibility to develop Multiple
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …
Immunopathogenesis of viral infections in neurological autoimmune disease
MA Habibi, F Nezhad Shamohammadi, T Rajaei… - BMC neurology, 2023 - Springer
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-
antigens. Several factors play a role in inducing autoimmunity, including genetic and …
antigens. Several factors play a role in inducing autoimmunity, including genetic and …
The enigmatic role of viruses in multiple sclerosis: molecular mimicry or disturbed immune surveillance?
Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …
Virus-induced autoimmune reactions in the CNS
Neurologic diseases are diverse and often not well-understood, despite the tremendous
health care problems they pose, such as the estimated 22 million persons worldwide who …
health care problems they pose, such as the estimated 22 million persons worldwide who …
The repertoire of CSF antiviral antibodies in patients with neuroinflammatory diseases
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). Although various viruses have been proposed to contribute to MS …
nervous system (CNS). Although various viruses have been proposed to contribute to MS …