The transient receptor potential vanilloid 1 receptor (TRPV1) plays an important role in
inflammatory heat hyperalgesia. TRPV1 is a non-selective cation channel gated by noxious …

Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation
channel expressed predominantly in peripheral nociceptors. By detecting and integrating …

BACKGROUND Chronic pain is a debilitating illness with currently limited therapy, in part
due to difficulties in translating treatments derived from animal models to patients. The …

Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a high-
conductance, nonselective cation channel strongly expressed in nociceptive primary afferent …

Transient receptor potential vanilloid 1 (TRPV1) is an ion channel present on sensory
neurons which is activated by heat, protons, capsaicin and a variety of endogenous lipids …

TRPV1 is a non-selective cation channel gated by noxious heat, vanilloids and extracellular
protons, and act as an important signal integrator in sensory nociceptors. Because of its …

The transient receptor potential vanilloid 4 (TRPV4) contributes to mechanical hyperalgesia
of diverse etiologies, presumably as part of a mechanoreceptor signaling complex. To …

Control of chronic pain is frequently inadequate and/or associated with intolerable adverse
effects, prompting a frantic search for new therapeutics and new therapeutic targets. Nearly …

In peripheral sensory neurons, the vanilloid receptor TRPV1 (transient receptor potential
vanilloid subfamily, member 1) functions as a molecular integrator of painful stimuli …

Background and Purpose Transient receptor potential vanilloid subtype 3 (TRPV3) is
implicated in nociception and certain skin conditions. As such, it is an attractive target for …