[HTML][HTML] Neuroprotective and Neurorestorative Effects of Holothuria scabra Extract in the MPTP/MPP+-Induced Mouse and Cellular Models of Parkinson's Disease

K Noonong, P Sobhon, M Sroyraya… - Frontiers in …, 2020 - frontiersin.org
Extracts from Holothuria scabra (HS) have been shown to possess anti-inflammation, anti-
oxidant and anti-cancer activities. More recently, it was shown to have neuroprotective …

[HTML][HTML] Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP+/MPTP Models of Parkinson's Disease In Vitro and In Vivo

YC Lo, YT Shih, YT Tseng, HT Hsu - … -Based Complementary and …, 2012 - hindawi.com
San-Huang-Xie-Xin-Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix, and
Rhei rhizoma, is a traditional Chinese medicine used for complementary and alternative …

Holothuria scabra extracts exhibit anti-Parkinson potential in C. elegans: A model for anti-Parkinson testing

P Chalorak, P Jattujan, S Nobsathian… - Nutritional …, 2018 - Taylor & Francis
Objectives: Parkinson's disease (PD) is associated with aggregation of α-synuclein and
selective death of dopaminergic (DA) neurons in the substantia nigra, thereby leading to …

Effects of hydroxysafflor yellow A in the attenuation of MPTP neurotoxicity in mice

B Han, H Zhao - Neurochemical research, 2010 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder whose etiology is not
understood. The 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-treated mouse …

[HTML][HTML] Anti-Parkinson activity of bioactive substances extracted from Holothuria leucospilota

N Malaiwong, P Chalorak, P Jattujan… - Biomedicine & …, 2019 - Elsevier
Parkinson's disease (PD) is a well-known neurodegenerative disorder characterized by
dopaminergic (DA) neuron loss and α-synuclein aggregation. Recent study revealed that the …

Protective effect of a novel herbmedicine, Hepad, on apoptosis of SH-SY5Y cells and a rat model of Parkinson's disease

SY Baek, NR Lee, DH Kim, A Gu, SY Kim… - Molecular & Cellular …, 2015 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of
dopaminergic neurons in the substantia nigra pars compacta. In this study, we investigated …

Protective effects of 2, 3, 5, 4′-tetrahydroxystilbene-2-O-β-d-glucoside in the MPTP-induced mouse model of Parkinson's disease: Involvement of reactive oxygen …

H He, S Wang, J Tian, L Chen, W Zhang, J Zhao… - European Journal of …, 2015 - Elsevier
Parkinson's disease (PD) is characterized by the selective death of dopaminergic neurons in
the substantia nigra pars compacta. Oxidative stress-induced neuron loss is thought to play …

[HTML][HTML] Mitigation effects of a novel herbal medicine, hepad, on neuroinflammation, neuroapoptosis, and neuro-oxidation

DH Song, GJ Kim, KJ Lee, JS Shin, DH Kim, BJ Park… - Molecules, 2018 - mdpi.com
Parkinson's disease (PD), a common adult-onset neurodegenerative disorder with complex
pathological mechanisms, is characterized by the degeneration of dopaminergic …

[HTML][HTML] Triple herbal extract DA-9805 exerts a neuroprotective effect via amelioration of mitochondrial damage in experimental models of Parkinson's disease

JS Jeong, Y Piao, S Kang, M Son, YC Kang, XF Du… - Scientific reports, 2018 - nature.com
Abstract Moutan cortex, Angelica Dahurica root, and Bupleurum root are traditional herbal
medicines used in Asian countries to treat various diseases caused by oxidative stress or …

Protection against MPP+-induced neurotoxicity in SH-SY5Y cells by tormentic acid via the activation of PI3-K/Akt/GSK3β pathway

Q Zhao, J Ye, N Wei, C Fong, X Dong - Neurochemistry International, 2016 - Elsevier
The cause of Parkinson's disease (PD) could be ascribed to the progressive and selective
loss of dopaminergic neurons in the substantia nigra pars compacta, and thus molecules …