Parkinson's disease (PD) is the second most prevalent progressive neurodegenerative
disease. Although several hypotheses have been proposed to explain the pathogenesis of …

Background Parkinson disease (PD) is a neurodegenerative disease characterized by the
loss of dopaminergic neurons in the substantia nigra (SN) and diminished dopamine content …

Parkinson's disease (PD) is a progressive neurodegenerative condition. The pathogenesis
of PD is still unknown, and drugs available for PD treatment either have side effects or have …

T-006, a new derivative of tetramethylpyrazine, has been recently found to protect against 6-
hydroxydopamine (6-OHDA)-induced neuronal damage and clear α-synuclein (α-syn) by …

Phytic acid (PA) is a naturally occurring constituent which exhibits protective action in
Parkinson's disease (PD). Inflammation in the central nervous system (CNS) is strongly …

The mechanisms underlying the neuroprotective effects of hesperidin in a murine model of
PD are not fully elucidated. The current study was carried out to investigate the ability of …

As a common progressive neurodegenerative disorder, the satisfied therapies for
Parkinson's disease (PD) are still unavailable. As a natural acetylcholinesterase inhibitor …

Parkinson's disease (PD) is a common, chronic, and debilitating neurodegenerative disorder
characterized by progressive loss of nigrostriatal dopaminergic neurons due to unknown …

Regulation of various signalling (Ras-MAPK, PI3K and AKT) pathways by augmented
activity of neurotrophic factors (NTFs) could prevent or halt the progress of dopaminergic …

Objective: The objective of this study was to investigate whether 70% aqueous ethanol
extract of San-Jia-Fu-Mai decoction extract (SJFMDE) could protect against 1-methyl-4 …