Neuroprotective Effects of Gagam‐Sipjeondaebo‐Tang, a Novel Herbal Formula, against MPTP‐Induced Parkinsonian Mice and MPP+‐Induced Cell Death in SH …

JH Ko, JH Lee, B Choi, JY Park… - Evidence‐Based …, 2018 - Wiley Online Library
Parkinson's disease is a neurodegenerative disease characterized by progressive cell death
of dopaminergic neuron and following neurological disorders. Gagam‐Sipjeondaebo‐Tang …

Protection by rhynchophylline against MPTP/MPP+-induced neurotoxicity via regulating PI3K/Akt pathway

M Zheng, M Chen, W Wang, M Zhou, C Liu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Isolated from Uncaria rhynchophylla (U.
rhynchophylla), rhynchophylline (Rhy) has been applied for treating diseases related to …

Potent effects of alkaloid-rich extract from Huperzia selago against sodium nitroprusside-evoked PC12 cells damage via attenuation of oxidative stress and apoptosis

AM Lenkiewicz, GA Czapski, H Jęsko… - Folia …, 2016 - termedia.pl
Imbalance between production and scavenging of free radicals and other reactive oxygen
species (ROS) is a component of many diseases, but it is especially important in aging …

Neuroprotective Effects of Lindleyin on Hydrogen Peroxide‐Induced Cell Injury and MPTP‐Induced Parkinson's Disease in C57BL/6 Mice

JJ Zhang, XR Shi, WW Lv, XL Zhou… - Evidence‐Based …, 2020 - Wiley Online Library
Oxidative stress (OS) is a crucial factor influencing the development of Parkinson's disease
(PD). Here we first reported that Lindleyin (Lin), one of the major components of rhubarb …

Neuroprotective effects of loganin on MPTP‐induced Parkinson's disease mice: Neurochemistry, glial reaction and autophagy studies

YD Xu, C Cui, MF Sun, YL Zhu, M Chu… - Journal of Cellular …, 2017 - Wiley Online Library
Parkinson's disease (PD) is a progressive neurodegenerative disease, involving resting
tremor and bradykinesia, for which no recognized therapies or drugs are available to halt or …

Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson's disease model of mice

P Haeri, A Mohammadipour, Z Heidari… - Anatomical science …, 2019 - Springer
Parkinson's disease is caused by damage to substantia nigra dopaminergic neurons.
Factors such as oxidative stress, inflammatory factors, and acetylcholinesterase activity may …

Cortex Fraxini (Qingpi) Protects Rat Pheochromocytoma Cells against 6‐Hydroxydopamine‐Induced Apoptosis

JJ Li, SY Zhou, H Zhang, KH Lam, SMY Lee… - Parkinson's …, 2015 - Wiley Online Library
Parkinson's disease (PD) is a chronic neurodegenerative disorder having close relationship
with oxidative stress induced by reactive oxygen species (ROS). Cortex Fraxini (QP) is a …

Lithospermic acid attenuates 1-methyl-4-phenylpyridine-induced neurotoxicity by blocking neuronal apoptotic and neuroinflammatory pathways

YL Lin, HJ Tsay, TH Lai, TT Tzeng, YJ Shiao - Journal of Biomedical …, 2015 - Springer
Background Parkinson's disease is the second most common neurodegenerative disorders
after Alzheimer's disease. The main cause of the disease is the massive degeneration of …

Hesperidin downregulates kinases lrrk2 and gsk3β in a 6-OHDA induced Parkinson's disease model

S Kesh, RR Kannan, K Sivaji, A Balakrishnan - Neuroscience letters, 2021 - Elsevier
The depletion of dopamine in the striatum region and Lewy bodies are the hallmark
characteristics of Parkinson's disease. The pathology also includes the upregulation of …

Antioxidant and anti-inflammatory potential of hesperidin against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced experimental Parkinson′ s disease in mice

K Tamilselvam, J Nataraj, U Janakiraman… - … Journal of Nutrition …, 2013 - journals.lww.com
Background: There is mounting evidence that flavonoid consumption is potentially beneficial
to those suffering from neurodegenerative diseases, cardiovascular disease, and cancer …