Regulation of AKT/AMPK signaling, autophagy and mitigation of apoptosis in Rutin-pretreated SH-SY5Y cells exposed to MPP+
Accumulating evidence suggest that apoptosis, autophagy and dysregulation of signaling
pathways are common mechanisms involved in Parkinson's disease (PD) pathogenesis …
pathways are common mechanisms involved in Parkinson's disease (PD) pathogenesis …
Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …
Mulberry fruit, which has been long used in traditional oriental medicine, was reported to
ameliorate motor dysfunction and dopaminergic neuronal degeneration via antioxidant and …
ameliorate motor dysfunction and dopaminergic neuronal degeneration via antioxidant and …
Protecting effect of Cistanche extracts on MPP+-induced injury of the Parkinson's disease cell model
H Wang, WW Li, DF Cai, R Yang - Zhong xi yi jie he xue bao …, 2007 - europepmc.org
Objective To investigate the potential protective role of Cistanche extracts on 1-methyl-4-
phenylpyridinium ion (MPP (+))-induced Parkinson's disease (PD) cellular model, and to find …
phenylpyridinium ion (MPP (+))-induced Parkinson's disease (PD) cellular model, and to find …
In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Δ3,2-hydroxybakuchiol isolated from Psoralea corylifolia (L.)
G Zhao, XW Zheng, GW Qin, Y Gai, ZH Jiang… - Cellular and Molecular …, 2009 - Springer
Cocktail recipes containing Psoralea corylifolia seeds (PCS) are used to empirically treat
Parkinson disease. A PCS isolate Δ 3, 2-hydroxybakuchiol (BU) can inhibit dopamine …
Parkinson disease. A PCS isolate Δ 3, 2-hydroxybakuchiol (BU) can inhibit dopamine …
A novel synthetic peptide SVHRSP attenuates dopaminergic neurodegeneration by inhibiting NADPH oxidase-mediated neuroinflammation in experimental models of …
X Zhang, D Tu, S Li, N Li, D Li, Y Gao, L Tian… - Free Radical Biology …, 2022 - Elsevier
Current treatment of Parkinson's disease (PD) ameliorates symptoms but fails to block
disease progression. This study was conducted to explore the protective effects of SVHRSP …
disease progression. This study was conducted to explore the protective effects of SVHRSP …
Neuroprotective effect of paeoniflorin in the mouse model of Parkinson's disease through α-synuclein/protein kinase C δ subtype signaling pathway
K Guo, Y Zhang, L Li, J Zhang, H Rong, D Liu… - …, 2021 - journals.lww.com
Objectives Paeoniflorin, an active component of Radix Paeoniae Alba, has a
neuroprotective effect in Parkinson's animal models. However, its mechanism of action …
neuroprotective effect in Parkinson's animal models. However, its mechanism of action …
Inhibition of γH2AX, COX-2 and regulation of antioxidant enzymes in MPP+-exposed SH-SY5Y cells pre-treated with rutin
Many plant-derived bioactive compounds such as rutin are reportedly effective in attenuating
neuronal death in most neurodegenerative disorders. Parkinson's disease (PD) is …
neuronal death in most neurodegenerative disorders. Parkinson's disease (PD) is …
Tenuigenin protects dopaminergic neurons from inflammation‐mediated damage induced by the lipopolysaccharide
HL Yuan, B Li, J Xu, Y Wang, Y He… - CNS neuroscience & …, 2012 - Wiley Online Library
Background P arkinson's disease (PD) is a neurodegenerative disorder characterized by
progressive death of dopaminergic neurons in the substantia nigra pars compacta (SN pc) …
progressive death of dopaminergic neurons in the substantia nigra pars compacta (SN pc) …
Lycopodium attenuates loss of dopaminergic neurons by suppressing oxidative stress and neuroinflammation in a rat model of Parkinson's disease
RL Jayaraj, R Beiram, S Azimullah, MFN Meeran… - Molecules, 2019 - mdpi.com
Parkinson's disease, a chronic, age related neurodegenerative disorder, is characterized by
a progressive loss of nigrostriatal dopaminergic neurons. Several studies have proven that …
a progressive loss of nigrostriatal dopaminergic neurons. Several studies have proven that …
Neuroprotective effects of Paeonia Lactiflora extract against cell death of dopaminergic SH-SY5Y cells is mediated by epigenetic modulation
G Lee, JC Joo, BY Choi, AM Lindroth, SJ Park… - … and alternative medicine, 2016 - Springer
Abstract Background The Paeonia lactiflora extract (PLE) has been reported to have
neuroprotective effect against neurodegeneration that are induced by cellular stress such as …
neuroprotective effect against neurodegeneration that are induced by cellular stress such as …