Advent of the acute respiratory coronavirus SARS-CoV-2 has resulted in the search for novel
antiviral agents and in the repurposing of existing agents with demonstrated efficacy against …

Several adamantanes have established actions against coronaviruses. Amantadine,
rimantadine, bananins and the structurally related memantine are effective against human …

Facing the outbreak of coronavirus disease 2019 (COVID-19) pandemic, there is an urgent
need to find protective or curable drugs to prevent or to stop the course of the coronavirus …

Introduction The aminoadamantanes amantadine and memantine are well known. They
mainly act as N-methyl-D-aspartate antagonists. Areas covered The antiviral drug …

Background and purpose Adamantanes were listed as an interesting option as an early
intervention against COVID‐19. We aimed to evaluate the effectiveness of amantadine in …

Background: Amantadine has been proposed to inhibit E-channel conductance in
reconstituted lipid bilayers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Background COVID-19, a disease caused by infection with the SARS-CoV-2 virus, is
asymptomatic or mildly symptomatic in most cases. Some patients, usually burdened with …

Coronavirus disease 2019 (COVID-19) has had devastating effects worldwide, with
particularly high morbidity and mortality in outbreaks on residential care facilities …

Background Amantadine is a drug that can help in the prevention of SARS-CoV-2
symptomatology, as has been demonstrated in observational clinical studies. Methods We …

The SARS-CoV-2 pandemic is causing the scientific community to look for the best treatment
to fight the virus. Studies are being carried out worldwide with this purpose looking into …