Patient-reported outcomes (PROs) from the Phase III IMbrave150 trial of atezolizumab (atezo)+ bevacizumab (bev) vs sorafenib (sor) as first-line treatment (tx) for …
476 Background: Atezo+ bev in pts with unresectable HCC who had not received prior
systemic therapy has shown statistically significant and clinically meaningful improvement in …
systemic therapy has shown statistically significant and clinically meaningful improvement in …
[HTML][HTML] IMbrave150: efficacy and safety results from a ph III study evaluating atezolizumab (atezo)+ bevacizumab (bev) vs sorafenib (Sor) as first treatment (tx) for …
Background Ph 1b data has shown promising efficacy and safety for atezo+ bev in
unresectable HCC pts who have not received prior systemic therapy. Here, we report the …
unresectable HCC pts who have not received prior systemic therapy. Here, we report the …
IMbrave150: Exploratory analysis to examine the association between treatment response and overall survival (OS) in patients (pts) with unresectable hepatocellular …
4071 Background: Based on IMbrave150 (NCT03434379) results, atezo+ bev has been
approved in> 60 countries for pts with unresectable HCC who have not received prior …
approved in> 60 countries for pts with unresectable HCC who have not received prior …
Updated safety and clinical activity results from a phase Ib study of atezolizumab+ bevacizumab in hepatocellular carcinoma (HCC)
MJ Pishvaian, MS Lee, BY Ryoo, S Stein… - Annals of …, 2018 - annalsofoncology.org
Background: Agents targeting angiogenesis or PD-L1/PD-1 signalling represent 2 types of
approved treatments (tx) for HCC. In addition to its anti-angiogenic activity, bevacizumab …
approved treatments (tx) for HCC. In addition to its anti-angiogenic activity, bevacizumab …
Patient-reported outcomes with atezolizumab plus bevacizumab versus sorafenib in patients with unresectable hepatocellular carcinoma (IMbrave150): an open-label …
PR Galle, RS Finn, S Qin, M Ikeda, AX Zhu… - The Lancet …, 2021 - thelancet.com
Background Understanding patients' experience of cancer treatment is important. We aimed
to evaluate patient-reported outcomes (PROs) with atezolizumab plus bevacizumab versus …
to evaluate patient-reported outcomes (PROs) with atezolizumab plus bevacizumab versus …
[HTML][HTML] Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma
Background & Aims IMbrave150 demonstrated that atezolizumab plus bevacizumab led to
significantly improved overall survival (OS) and progression-free survival (PFS) compared …
significantly improved overall survival (OS) and progression-free survival (PFS) compared …
Characterization of response to atezolizumab+ bevacizumab versus sorafenib for hepatocellular carcinoma: Results from the IMbrave150 trial
R Salem, D Li, N Sommer, S Hernandez… - Cancer …, 2021 - Wiley Online Library
Background IMbrave150 is a phase III trial that assessed atezolizumab+ bevacizumab
(ATEZO/BEV) versus sorafenib (SOR) in patients with unresectable hepatocellular …
(ATEZO/BEV) versus sorafenib (SOR) in patients with unresectable hepatocellular …
Clinical value of atezolizumab+ bevacizumab for first-line unresectable hepatocellular carcinoma (HCC): A network meta-analysis.
A Vogel, L Rimassa, HC Sun, GK Abou-Alfa… - 2020 - ascopubs.org
4585 Background: The IMbrave150 pivotal study in unresectable HCC showed superiority of
atezolizumab+ bevacizumab (atezo+ bev) vs sorafenib for OS and PFS. Based on these …
atezolizumab+ bevacizumab (atezo+ bev) vs sorafenib for OS and PFS. Based on these …
IMbrave150: A randomized phase III study of 1L atezolizumab plus bevacizumab vs sorafenib in locally advanced or metastatic hepatocellular carcinoma.
TPS4141 Background: Hepatocellular carcinoma (HCC) is a lethal disease with the highest
mortality-to-incidence ratio of any solid tumor. The current standard of care for 1L treatment …
mortality-to-incidence ratio of any solid tumor. The current standard of care for 1L treatment …
Updated efficacy and safety data from IMbrave150: atezolizumab plus bevacizumab vs. Sorafenib for unresectable hepatocellular carcinoma
A Roy - Journal of Clinical and Experimental Hepatology, 2022 - jcehepatology.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and remains a
significant cause of cancerrelated death globally. The incidence of HCC has been on the …
significant cause of cancerrelated death globally. The incidence of HCC has been on the …
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