5-Isopropyl-2-methylphenol enhances penile function in spontaneously hypertensive rats

TAF Gonçalves, PMP Maciel… - Journal of Applied …, 2024 - japsonline.com
Isopropyl-2-methylphenol, a monoterpene found in essential oils from various plants, has
been shown to have anti-inflammatory, antioxidant, vasorelaxant, and hypotensive effects …

Carvacrol Improves Erectile Dysfunction in Spontaneously Hypertensive Rats

T Gonçalves, P Maciel, L Villanueva, P Santos… - 2019 - europepmc.org
Carvacrol is a monoterpene found in essential oils from various plants. Several
pharmacological properties have already been described for carvacrol, including …

Effects of sildenafil on human penile blood vessels

P Medina, G Segarra, JM Vila, C Domenech… - Urology, 2000 - Elsevier
Objectives. To investigate the effects of sildenafil on human penile blood vessels and
evaluate the interaction of sildenafil with neurogenic-mediated responses. Sildenafil is …

[HTML][HTML] THE BENEFICIAL EFFECT OF INTRACAVERNOSAL INJECTION OF SILDENAFIL ON ERECTILE DYSFUNCTION IN DUTASTERIDE TREATED RATS

DY Oral, S Gur - Journal of Faculty of Pharmacy of Ankara University, 2022 - dergipark.org.tr
Objective: Benign prostatic hyperplasia (BPH) and erectile dysfunction (ED) are the most
common illnesses in aged male patients. 5α-reductase inhibitors (5-ARIs) are suggested for …

Yohimbine enhances the effect of sildenafil on erectile process in rats

AM Senbel, T Mostafa - International journal of impotence research, 2008 - nature.com
Combining the centrally acting drug yohimbine with the peripheral conditioner sildenafil
might be an approach to erectile dysfunction cases in which sildenafil alone failed. This work …

Chronic administration of fluoxetine impairs neurogenic and endothelium-dependent relaxation of the rabbit corpus cavernosum smooth muscle

SS Göçmez, T Utkan, N Gacar, Y Sarioglu - European journal of …, 2011 - Elsevier
Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), cause erectile
dysfunction; however, the mechanism by which they cause erectile function is unclear. We …

Potential effects of yohimbine and sildenafil on erectile dysfunction in rats

MA Saad, NI Eid, HA Abd El-Latif, HM Sayed - European journal of …, 2013 - Elsevier
In this study the effects of yohimbine and sildenafil on cold stress-induced erectile
dysfunction in rats were investigated. Yohimbine hydrochloride (0.2 mg/kg, ip) and sildenafil …

Comparative effects of sildenafil, phentolamine, yohimbine and l‐arginine on the rabbit corpus cavernosum

FM Sharabi, TT Daabees… - Fundamental & …, 2004 - Wiley Online Library
Penile erection involves relaxation of smooth muscle of corpus cavernosum and associated
arterioles. Sildenafil, a highly selective inhibitor of phosphodiesterase type 5, is effective in …

Pharmacological profiles of sildenafil (VIAGRA) in the treatment of erectile dysfunction: efficacy and drug interaction with nitrate

M Omote - Nihon yakurigaku zasshi. Folia pharmacologica …, 1999 - europepmc.org
Penile erection follows relaxation of the corpus cavernosum in which nitric oxide (NO)
released during sexual stimulation from non-adrenergic non-cholinergic nerve endings and …

Combined effect of sildenafil and guanethidine, propranolol or verapamil on erectile function in rats

AM Senbel, AM Hashad, FM Sharabi… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives This study aims to further elucidate the role of adrenergic transmission in erection
and to highlight whether adrenergic transmission in the penis modulates sildenafil's action …