The Rho-kinase pathway mediates Ca2+ sensitization in the penile circulation, which
maintains the penis in the flaccid state. We aimed to investigate the functional effect of a …

Abstract Treatment of erectile dysfunction (ED) in hypertensive subjects remains to be
formally established. There is currently no standardized treatment for ED in hypertensive …

The relaxant effect of methanolic extract of yohimbe bark (Pausinystalia yohimbe) on rabbit
corpus cavernosum smooth muscles Page 1 Vol.4, No.9, 656-659 (2012) Health http://dx.doi.org/10.4236/health.2012.49103 …

The role of phosphodiesterase type 5 inhibition in the modulation of female sexual
dysfunction was investigated by assessing its effects on in vitro relaxation of rabbit clitoris …

Abstract Development and maintenance of penile erection requires the relaxation of the
smooth muscle cells in the cavernous bodies and is essentially mediated by nitric oxide …

The present study examined functional effects of a new selective phosphodiesterase type 5
inhibitor, 1-[4-ethoxy-3-(6, 7-dihydro-1-methyl-7-thioxo-3-propyl-1H-pyrazolo [4, 3] pyrimidin …

RESULTS: The penile weight of the bilaterally denervated group was significantly lower than
sham group. Sildenafil treatment had positive effects on penile weight of both bilaterally (p …

The primate model has been used for investigations on the physiology and pharmacology of
erection. Recent in vitro investigations indicate that nitric oxide (NO)‐donor act as the …

Purpose: The effects of sildenafil, a highly selective inhibitor of cyclic guanosine
monophosphate-specific phosphodiesterase type 5, on erectile function in the anesthetized …

Aim To study the effects of exogenous excess of testosterone on the constricting effect of
phenylephrine and endothelium-dependent and-independent relaxing effects of different …