A 4 gene-based immune signature predicts dedifferentiation and immune exhaustion in thyroid cancer

CW Li, X Shi, B Ma, YL Wang, ZW Lu… - The Journal of …, 2021 - academic.oup.com
Context The role of immune-related genes (IRGs) in thyroid cancer dedifferentiation and
accompanying immune exhaustion remains largely unexplored. Objective To construct a …

Identification of an immune-related signature indicating the dedifferentiation of thyroid cells

X Wang, W Peng, C Li, R Qin, Z Zhong, C Sun - Cancer Cell International, 2021 - Springer
Background Immune cells account for a large proportion of the tumour microenvironment in
anaplastic thyroid carcinomas (ATCs). However, the expression pattern of immune-related …

[HTML][HTML] Development of a prognostic index based on an immunogenomic landscape analysis of papillary thyroid cancer

P Lin, Y Guo, L Shi, X Li, H Yang, Y He, Q Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer,
and inflammation relates significantly to its initiation and prognosis. Systematic exploration …

Diagnosis and prognosis of thyroid cancer by immune-related genes

J Li, Z Li, P Zhao - American Journal of Clinical Oncology, 2024 - journals.lww.com
Background: Thyroid carcinoma (THCA) is the most common malignant endocrine tumor
with low mortality and a relatively good prognosis. Immune genes have attracted much …

Immune landscape of papillary thyroid cancer and immunotherapeutic implications

KJ Na, H Choi - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …

Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma

R Qin, C Li, X Wang, Z Zhong, C Sun - Cancer Cell International, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the most common pathological type of
thyroid cancer. The effect of traditional anti-tumor therapy is not ideal for the patients with …

Characterization of immune landscape in papillary thyroid cancer reveals distinct tumor immunogenicity and implications for immunotherapy

J Sun, R Shi, X Zhang, D Fang, J Rauch, S Lu… - …, 2021 - Taylor & Francis
Although the vast majority of patients with papillary thyroid cancer (PTC) have a favorable
prognosis when conventional treatments are implemented, local recurrence and distant …

[HTML][HTML] Immune gene signature delineates a subclass of thyroid cancer with unfavorable clinical outcomes

J Zhi, J Yi, M Tian, H Wang, N Kang, X Zheng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Thyroid cancer (THCA) is a heterogeneous disease with multiple clinical outcomes Immune
cells regulate its progression. Three immunomolecular subtypes (C1, C2, C3) were …

An immune-related prognostic signature for thyroid carcinoma to predict survival and response to immune checkpoint inhibitors

P Wu, W Sun, H Zhang - Cancer Immunology, Immunotherapy, 2022 - Springer
Thyroid carcinoma (THCA) is the most common endocrine malignancy, and its incidence is
increasing worldwide. Several studies have explored whether the tumor immune …

Characterization of the immune cell infiltration landscape of thyroid cancer for improved immunotherapy

J Gong, B Jin, L Shang, N Liu - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Within the endocrine system, thyroid cancer (THCA) is the most typical malignant tumor.
Tumor-infiltrating immune cells play vital roles in tumor progression, recurrence, metastasis …