Clinical studies as well as animal models emphasized the importance of the complement
system in the pathogenesis of coronary atherosclerosis and cardiovascular diseases. Our …

The aim of this study was to determine whether complement C3 is an indicator of coronary
artery disease (CAD). We measured plasma C3 and CRP levels in 278 patients undergoing …

Background and objectives The complement system plays an important role in the
development of acute coronary syndrome (ACS). Complement C1q is an important initial …

Atherosclerosis is an inflammatory disease. The complement system plays an important role
in the atherosclerotic process. However, lesser data is available on the possible role of C3 …

OBJECTIVE: The complement system is activated in human atherosclerotic lesions and may
hence aggravate local inflammation. We studied the presence and localization of C4b …

Background The mechanisms underlying early atherosclerotic plaque formation are not
completely understood. Moreover, plasma biomarkers of subclinical atherosclerosis are …

Studies conducted in animal models have suggested that membrane complement regulatory
proteins play an important role in the pathophysiology of coronary artery disease (CAD). In …

Background: Complement C1q plays a dual role in the atherosclerosis. Previous studies
showed inconsistent results about the association of serum C1q levels and coronary artery …

While complement is the most important component of humoral autoimmunity, and
inflammation plays a key role in atherosclerosis, relatively few studies have looked at …

Acute coronary syndrome is an inflammatory disease, during which the complement
cascade is activated. We assessed the complement C3 and C4 concentration ratio (C3/C4 …