Lysosome, an important organelle in eukaryotes, can sequester macromolecules submitted
by the endocytosis and autophagy pathways for degradation and recycling. Massive …

Accompanying the precipitous age-related decline in human female fertility is an increase in
the proportion of poor-quality oocytes within the ovary. The macroautophagy pathway, an …

While a critical role of autophagy in mammalian early embryogenesis has been
demonstrated, few studies have been conducted regarding the role of autophagy in in vitro …

Autophagy is an essential cellular mechanism that degrades cytoplasmic proteins and
organelles to recycle their components; however, the contribution of autophagy during …

In females, the establishment of the primordial follicle pool is accompanied by a remarkable
programmed oocyte loss for unclear reasons. In this study, the role of autophagy was …

Around the time of oocyte meiotic arrest, germ cell nest breakdown occurs, and primordial
follicle (PF) formation is initiated at the perinatal stage. Recently, autophagy was implicated …

Post‐ovulatory aging of oocytes results in the progressive loss of fertilization and
developmental competence. This degradation of oocyte quality has been the object of …

Supporting cells of oocytes, ie, cumulus cells, control oocyte quality, which determines
fertilization success. Therefore, the transformation of mature and immature cumulus cells …

ABSTRACT PLD1 has been implicated in cytoskeletal reorganization and vesicle trafficking
in somatic cells; however, its function remains unclear in oocyte meiosis. Herein, we found …

Autophagy, an intracellular recycling system, is essential for the meiotic maturation of
porcine oocytes. Trehalose has been reported as a novel mammalian target of rapamycin …