Current position on the role of monomeric C-reactive protein in vascular pathology and atherothrombosis

IS Melnikov, SG Kozlov, OS Saburova… - Current …, 2020 - ingentaconnect.com
C-reactive Protein (CRP) is an acute phase reactant, belonging to the pentraxin family of
proteins. Its level rises up to 1000-fold in response to acute inflammation. High sensitivity …

C-reactive protein and the biology of disease

W Ansar, S Ghosh - Immunologic research, 2013 - Springer
The C-reactive protein (CRP) is a plasma protein of hepatic origin, belonging to pentraxin
family and forms a major component of any inflammatory reaction. A key component of the …

[HTML][HTML] C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit

K Kirkgöz - Reviews in Cardiovascular Medicine, 2023 - imrpress.com
C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to
inflammatory cytokines. It exists in two functionally and structurally distinct isoforms. The first …

C-reactive protein in atherothrombosis and angiogenesis

L Badimon, E Peña, G Arderiu, T Padró… - Frontiers in …, 2018 - frontiersin.org
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation,
or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions. This …

[PDF][PDF] Two Forms of C-Reactive Protein and Their Implication for Atherogenesis: Focus on Monomeric Form

AV Poznyak, VA Khotina… - Journal of …, 2024 - publishing.emanresearch.org
In this review, we discuss the role of C-reactive protein (CRP), a biomarker of inflammation,
in the development of atherosclerosis. CRP exists in two forms: the native pentameric form …

Biology and relevance of C-reactive protein in cardiovascular and renal disease

J Westhuyzen, H Healy - Annals of Clinical & Laboratory …, 2000 - Assoc Clin Scientists
C-reactive protein (CRP) is a member of the pentraxin family of proteins, which are
characterised by a cyclic pentameric structure and radial symmetry. The five identical 24 …

C-reactive protein and its structural isoforms: an evolutionary conserved marker and central player in inflammatory diseases and beyond

JD McFadyen, J Zeller, LA Potempa… - … , lipoproteins and other …, 2020 - Springer
C-reactive protein (CRP) is an evolutionary highly conserved member of the pentraxin
superfamily of proteins. CRP is widely used as a marker of inflammation, infection and for …

C‐reactive protein: an in‐depth look into structure, function, and regulation

J Salazar, MS Martínez… - International …, 2014 - Wiley Online Library
Cardiovascular disease is the leading cause of morbidity and mortality in the adult
population worldwide, with atherosclerosis being its key pathophysiologic component …

Monomeric C-reactive protein–a feature of inflammatory disease associated with cardiovascular pathophysiological complications?

Y Zeinolabediny, S Kumar, M Slevin - in vivo, 2021 - iv.iiarjournals.org
Monomeric C-reactive protein (mCRP), the dissociated form of native C-reactive protein, is a
critical molecule that causes and perpetuates inflammation in serious diseases. It has …

Monomeric C-reactive protein in atherosclerotic cardiovascular disease: advances and perspectives

I Melnikov, S Kozlov, O Saburova, Y Avtaeva… - International journal of …, 2023 - mdpi.com
This review aimed to trace the inflammatory pathway from the NLRP3 inflammasome to
monomeric C-reactive protein (mCRP) in atherosclerotic cardiovascular disease. CRP is the …