[HTML][HTML] Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease

V Lepoutre, P Jain, K Quann, B Wigdahl… - Frontiers in bioscience …, 2009 - ncbi.nlm.nih.gov
Human T cell leukemia virus type 1 (HTLV-1) is a type C retrovirus primarily endemic to
Japan, Central and South America, the Middle East, regions of Africa, and the Caribbean (1 …

Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease

N Araya, T Sato, N Yagishita, H Ando, A Utsunomiya… - Viruses, 2011 - mdpi.com
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that is the causative agent of
adult T cell leukemia/lymphoma (ATL) and associated with multiorgan inflammatory …

Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder

Y Yamano, N Araya, T Sato, A Utsunomiya, K Azakami… - PloS one, 2009 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus associated
with both HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which is a …

Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

[PDF][PDF] Immunopathogensis of HTLV-I associated neurologic disease: molecular, histopathologic, and immunologic approaches

N Takenouchi, K Yao, S Jacobson - Front Biosci, 2004 - article.imrpress.com
Introduction 3. Risk factors for development of HAM/TSP 3.1. Variants of the virus 3.2. HTLV-I
proviral load 3.3. Host genetic factors 4. Pathological analysis in HAM/TSP 4.1 …

Lessons from the cerebrospinal fluid analysis of HTLV-1-infected individuals: biomarkers of inflammation for HAM/TSP development

NL Freitas, YCP Gomes, FS Souza, RC Torres… - Viruses, 2022 - mdpi.com
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a
neurodegenerative disease that leads to motor impairment due to a chronic inflammatory …

HTLV-1 infection of myeloid cells: from transmission to immune alterations

B Rocamonde, A Carcone, R Mahieux, H Dutartre - Retrovirology, 2019 - Springer
Human T cell leukemia virus type 1 (HTLV-1), the etiological agent of adult T-cell
leukemia/lymphoma (ATLL) and the demyelinating neuroinflammatory disease known as …

Visualization of HTLV-1–specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1–associated myelopathy/tropical spastic Paraparesis

E Matsuura, R Kubota, Y Tanaka… - … of Neuropathology & …, 2015 - academic.oup.com
Activated human T-lymphotropic virus type-1 (HTLV-1)–specific CD8-positive cytotoxic T
lymphocytes (CTLs) are markedly increased in the periphery of patients with HTLV-1 …

Lower numbers of circulating natural killer T (NK T) cells in individuals with human T lymphotropic virus type 1 (HTLV-1) associated neurological disease

LC Ndhlovu, JE Snyder-Cappione… - Clinical & …, 2009 - academic.oup.com
Human T lymphotropic virus type 1 (HTLV-1) infects 10–20 million people worldwide. The
majority of infected individuals are asymptomatic; however, approximately 3% develop the …

Impaired function of human T-lymphotropic virus type 1 (HTLV-1)–specific CD8+ T cells in HTLV-1–associated neurologic disease

AH Sabouri, K Usuku, D Hayashi… - Blood, The Journal …, 2008 - ashpublications.org
Despite abundant activated virus-specific cytotoxic T lymphocytes (CTLs), patients with
human T-lymphotropic virus type 1 (HTLV-1)–associated myelopathy/tropical spastic …