[HTML][HTML] LncRNA-dependent mechanisms of transforming growth factor-β: from tissue fibrosis to cancer progression

PCT Tang, YY Zhang, JSF Li, MKK Chan, J Chen… - Non-coding RNA, 2022 - mdpi.com
Transforming growth factor-β (TGF-β) is a crucial pathogenic mediator of inflammatory
diseases. In tissue fibrosis, TGF-β regulates the pathogenic activity of infiltrated …

[HTML][HTML] LncRNAs in TGF-β-driven tissue fibrosis

PMK Tang, YY Zhang, HY Lan - Non-coding RNA, 2018 - mdpi.com
Transforming growth factor-β (TGF-β) is a crucial mediator in tissue fibrosis that promotes
accumulation of extracellular matrix (ECM), myofibroblasts to epithelial–mesenchymal …

[HTML][HTML] Roles of TGF‑β signalling pathway‑related lncRNAs in cancer

Z Hu, Y Liu, M Liu, Y Zhang… - Oncology Letters, 2023 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are a class of RNAs that are> 200 nucleotides in length
that do not have the ability to be translated into protein but are associated with numerous …

Crosstalk between transforming growth factor-β signaling pathway and long non-coding RNAs in cancer

J Wang, N Shao, X Ding, B Tan, Q Song, N Wang, Y Jia… - Cancer letters, 2016 - Elsevier
The transforming growth factor-β (TGF-β) signaling pathway plays an important role in
tumorigenesis by exerting either a tumor-suppressing or tumor-promoting effect. Long non …

[HTML][HTML] Pleiotropic roles of non-coding RNAs in TGF-β-mediated epithelial-mesenchymal transition and their functions in tumor progression

S Grelet, A McShane, R Geslain, PH Howe - Cancers, 2017 - mdpi.com
Epithelial-mesenchymal transition (EMT) is a spatially-and temporally-regulated process
involved in physiological and pathological transformations, such as embryonic development …

[HTML][HTML] Role of long non-coding RNAs and TGF-β signaling in the regulation of breast cancer pathogenesis and therapeutic targets

BM Hussen, HJ Hidayat, SR Abdullah, S Mohamadtahr… - Cytokine, 2023 - Elsevier
The cytokine known as transforming growth factor (TGF) is essential for cell development,
differentiation, and apoptosis in BC. TGF-β dysregulation can either promote or inhibit tumor …

[HTML][HTML] Regulation of TGFβ/SMAD signaling by long non-coding RNAs in different cancers: Dark Knight in the Castle of molecular oncology

A Adylova, AA Mukhanbetzhanovna, R Attar… - Non-coding RNA …, 2021 - Elsevier
One of the complex themes in recent years has been the multi-layered regulation of TGFβ
signaling in cancer cells. TGFβ/SMAD signaling pathway is a highly complicated web of …

The long (lncRNA) and short (miRNA) of it: TGFβ-mediated control of RNA-binding proteins and noncoding RNAs

H Janakiraman, RP House, VK Gangaraju… - Molecular Cancer …, 2018 - AACR
RNA-binding proteins (RBP) and noncoding RNAs (ncRNA), such as long noncoding RNAs
(lncRNA) and microRNAs (miRNA), control co-and posttranscriptional gene regulation …

[HTML][HTML] Long non-coding RNAs (LncRNA) regulated by transforming growth factor (TGF) β: LncRNA-hit-mediated TGFβ-induced epithelial to mesenchymal transition …

EJ Richards, G Zhang, ZP Li, J Permuth-Wey… - Journal of Biological …, 2015 - ASBMB
Long noncoding RNAs (lncRNAs) are emerging as key regulators in various biological
processes. Epithelial-to-mesenchymal transition (EMT) is a developmental process hijacked …

Long non‐coding RNAs and TGF‐β signaling in cancer

P Papoutsoglou, A Moustakas - Cancer Science, 2020 - Wiley Online Library
Cancer is driven by genetic mutations in oncogenes and tumor suppressor genes and by
cellular events that develop a misregulated molecular microenvironment in the growing …