Effect of the C1473G polymorphic variant of the tryptophan hydroxylase 2 gene and photoperiod length on the dopamine system of the mouse brain

NA Sinyakova, EY Bazhenova, EA Kulikova… - Molecular Biology, 2020 - Springer
A decrease in the light in autumn and winter causes depression like seasonal affective
disorders (SAD) in sensitive patients, in which the serotonin (5-HT) and dopamine (DA) …

Effect of photoperiodic alterations on depression-like behavior and the brain serotonin system in mice genetically different in tryptophan hydroxylase 2 activity

EY Bazhenova, DV Fursenko, EA Kulikova… - Neuroscience …, 2019 - Elsevier
Reduction of natural illumination in fall/winter months causes seasonal affective disorders
(SAD) in vulnerable individuals. Neurotransmitter serotonin (5-HT) is involved in the …

Tryptophan hydroxylase 2 in seasonal affective disorder: underestimated perspectives?

AV Kulikov, NK Popova - Reviews in the Neurosciences, 2015 - degruyter.com
Seasonal affective disorder (SAD) is characterized by recurrent depression occurring
generally in fall/winter. Numerous pieces of evidence indicate the association of SAD with …

Photoperiod regulates the daily profiles of tryptophan hydroxylase-2 gene expression the raphe nuclei of rats

ZS Malek, LM Labban - International Journal of Neuroscience, 2021 - Taylor & Francis
Abstract ِAim Tryptophan hydroxylase-2 mRNA (TPH, the rate limiting enzyme in 5-HT
synthesis) expression levels display circadian variations in the median and dorsal raphe …

Photoperiod regulates the daily profiles of tryptophan hydroxylase-2 gene expression the raphe nuclei of rats

L Labban, Z Malek - International Journal of Current Research in …, 2020 - ijcrpp.com
Abstract Tryptophan hydroxylase-2 mRNA (TPH, the rate limiting enzyme in 5-HT synthesis)
expression levels display circadian variations in the median and dorsal raphe nuclei. This …

FC29-05-Season, sunlight, and brain serotonin function

N Praschak-Rieder, M Willeit, H Sitte, JH Meyer… - European …, 2011 - Elsevier
Introduction Many experience low mood and energy during winter. Brain serotonin is
involved in the regulation of many physiologic and pathologic functions that vary with …

Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor gene

E Molnar, J Lazary, A Benko, X Gonda, D Pap… - European …, 2010 - Elsevier
Seasonal Affective Disorder (SAD), seasonality and increased sensitivity to the fluctuation of
seasons in biological and psychological parameters can manifest to varying degrees across …

Diagnostic features, epidemiology, and pathophysiology of seasonal affective disorder

E Molnár, X Gonda, Z Rihmer… - Psychiatria Hungarica: A …, 2010 - europepmc.org
Seasonal Affective Disorder (SAD) is characterized by patterns of major depressive
episodes that occur and remit with the change of seasons. Two seasonal patterns have …

[HTML][HTML] Effect of Short Photoperiod on Behavior and Brain Plasticity in Mice Differing in Predisposition to Catalepsy: The Role of BDNF and Serotonin System

S Adonina, E Bazhenova, D Bazovkina - International Journal of …, 2024 - mdpi.com
Seasonal affective disorder is characterized by depression during fall/winter as a result of
shorter daylight. Catalepsy is a syndrome of some grave mental diseases. Both the …

Behavioral effects of tryptophan depletion in seasonal affective disorder associated with the serotonin transporter gene?

E Lenzinger, A Neumeister, N Praschak-Rieder… - Psychiatry …, 1999 - Elsevier
There is some evidence that the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) may
be involved in the pathogenesis of seasonal affective disorder (SAD). Short-term tryptophan …