In adapting to the intracellular niche, obligate intracellular bacteria usually undergo a
reduction of genome size by eliminating genes not needed for intracellular survival. These …

Persistence has evolved as a potent survival strategy to overcome adverse environmental
conditions. This capability is common to almost all bacteria, including all human bacterial …

Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

In a recent paper published in Frontiers in Microbiology, Ramisetty et al.(2016) questioned
the mainstream model regarding bacterial persistence proposed by the group of K. Gerdes …

Persisters are nongrowing, transiently antibiotic-tolerant bacteria within a clonal population
of otherwise susceptible cells. Their formation is triggered by environmental cues and …

Persistence is the non-heritable state of dormancy of a small subset of cells that allows these
cells to survive a wide range of stresses. These stresses include antibiotics at concentrations …

Certain bacterial pathogens are able to evade the host immune system and persist within
the human host. The consequences of persistent bacterial infections potentially include …

The increase in antibiotic non-responsive bacteria is the leading concern in current research
oriented to eliminate pathogens. Nowadays, the excess use of antibiotics without specifically …

Bacteria withstand antibiotic onslaughts by employing a variety of strategies, one of which is
persistence. Persistence occurs in a bacterial population where a subpopulation of cells …

As a clinician, Eleftherios Mylonakis saw first-hand the problems of bacterial persistence:
Patients who were treated for infections, particularly those caused by Staphylococcus …