A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?
X Xu, D Shen, Y Gao, Q Zhou, Y Ni, H Meng… - Translational …, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving
both upper and lower motor neurons, leading to paralysis and eventually death …
both upper and lower motor neurons, leading to paralysis and eventually death …
Therapeutic development in amyotrophic lateral sclerosis
M Bucchia, A Ramirez, V Parente, C Simone… - Clinical …, 2015 - Elsevier
Purpose Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
Current view and perspectives in amyotrophic lateral sclerosis
S Mathis, P Couratier, A Julian, P Corcia… - Neural Regeneration …, 2017 - journals.lww.com
Amyotrophic lateral sclerosis (ALS), identified as a distinct clinical entity by Charcot since the
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …
end of the nineteenth century, is a devastating and fatal neurodegenerative disorder that …
Development of novel treatments for amyotrophic lateral sclerosis
Z Sun, B Zhang, Y Peng - Metabolic Brain Disease, 2024 - Springer
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that causes
paralysis whose etiology and pathogenesis have not been fully elucidated. Presently it is …
paralysis whose etiology and pathogenesis have not been fully elucidated. Presently it is …
[HTML][HTML] Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
LM Gittings, R Sattler - Faculty reviews, 2020 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is
characterized by degeneration of both upper and lower motor neurons and subsequent …
characterized by degeneration of both upper and lower motor neurons and subsequent …
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …
Amyotrophic lateral sclerosis: current therapeutic perspectives
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …
progressive motor neuron degeneration, muscle weakness, paralysis, and ultimately death …
Amyotrophic lateral sclerosis–looking for pathogenesis and effective therapy
E Naganska, E Matyja - Folia Neuropathologica, 2011 - termedia.pl
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …
Understanding ALS: new therapeutic approaches
A Musarò - The FEBS journal, 2013 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …
Pharmacotherapy for amyotrophic lateral sclerosis: a review of approved and upcoming agents
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
involving loss of upper and lower motor neurons, with most cases ending in death within 3–5 …
involving loss of upper and lower motor neurons, with most cases ending in death within 3–5 …