Results from a multicentre international registry of familial Mediterranean fever: impact of environment on the expression of a monogenic disease in children

S Ozen, E Demirkaya, G Amaryan… - Annals of the …, 2014 - ard.bmj.com
Background and aim Familial Mediterranean fever (FMF) is an autoinflammatory disease
caused by mutations of the MEFV gene. We analyse the impact of ethnic, environmental and …

Familial Mediterranean fever in heterozygotes: are we able to accurately diagnose the disease in very young children?

V Hentgen, G Grateau… - Arthritis & …, 2013 - Wiley Online Library
Objective Familial Mediterranean fever (FMF) is an autosomal‐recessive autoinflammatory
disease due to mutations in MEFV. Descriptions of disease manifestations among patients …

Familial Mediterranean fever in childhood: a single-center experience

K Barut, S Sahin, A Adrovic, AB Sinoplu… - Rheumatology …, 2018 - Springer
The aim of this study is to present demographic and clinical features, MEFV mutation
variations, and treatment response of a large number of pediatric familial Mediterranean …

Real-life data from the largest pediatric familial Mediterranean fever cohort

K Öztürk, T Coşkuner, E Baglan, HE Sönmez… - Frontiers in …, 2022 - frontiersin.org
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease manifesting phenotypic heterogeneity. It is a clinically diagnosed disease supported …

Comparison of early versus late onset familial Mediterranean fever

NS Yasar Bilge, I Sari, D Solmaz… - International Journal …, 2018 - Wiley Online Library
Abstract Aim Familial Mediterranean fever (FMF) is the most common autoinflammatory
disease. One of the common characteristics of this disease is its young age predominance …

Mutations in the gene for familial Mediterranean fever: do they predispose to inflammation?

S Ozen, A Bakkaloglu, E Yilmaz, A Duzova… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To analyze 70 individuals who were found to have the Mediterranean fever
(MEFV) gene for the presence of definite familial Mediterranean fever (FMF) and to assess if …

The clinical and genetical features of 124 children with Familial Mediterranean fever: experience of a single tertiary center

A Inal, M Yilmaz, SG Kendirli, DU Altintas… - Rheumatology …, 2009 - Springer
The aim of the present study was to evaluate the clinical features of childhood-onset Familial
Mediterranean fever (FMF) patients and to assess the phenotype–genotype correlation. The …

Clinical and diagnostic value of genetic testing in 216 Israeli children with Familial Mediterranean fever.

S Padeh, Y Shinar, E Pras, D Zemer… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: Familial Mediterranean fever (FMF) is an autosomal recessive disease with
diverse clinical presentation. The FMF gene (MEFV) has recently been cloned and 30 point …

Comorbidities in familial Mediterranean fever: analysis of 2000 genetically confirmed patients

B Balcı-Peynircioğlu, Ü Kaya-Akça, ZS Arıcı… - …, 2020 - academic.oup.com
Objectives FMF is the most common periodic fever syndrome, characterized by recurrent
episodes of fever and serosal inflammation accompanied with high acute phase reactants …

Is age associated with disease severity and compliance to treatment in children with familial Mediterranean fever?

HE Sönmez, P Esmeray, ED Batu, ZS Arıcı… - Rheumatology …, 2019 - Springer
Abstract Familial Mediterranean Fever (FMF) is the most common monogenic
autoinflammatory disease in the world. The disease characteristics may vary in different age …