Nanoparticles for drug delivery in Parkinson's disease

J Baskin, JE Jeon, SJG Lewis - Journal of Neurology, 2021 - Springer
Although effective symptomatic treatments for Parkinson's disease (PD) have been available
for some time, efficient and well-controlled drug delivery to the brain has proven to be …

Drug development in Parkinson's disease: from emerging molecules to innovative drug delivery systems

E Garbayo, E Ansorena, MJ Blanco-Prieto - Maturitas, 2013 - Elsevier
Current treatments for Parkinson's disease (PD) are aimed at addressing motor symptoms
but there is no therapy focused on modifying the course of the disease. Successful treatment …

Micro-and nanotechnology approaches to improve Parkinson's disease therapy

PV Torres-Ortega, L Saludas, AS Hanafy… - Journal of controlled …, 2019 - Elsevier
Current therapies for Parkinson's disease are symptomatic and unable to regenerate the
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …

Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain

G Leyva-Gomez, H Cortes, JJ Magana… - Drug discovery today, 2015 - Elsevier
Highlights•We describe the main clinical manifestations and pathogenesis of Parkinson's
disease.•We present a general overview of current treatments for Parkinson's disease.•We …

Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles

A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Abstract Parkinson's disease (PD), although being the second most prevalent
neurodegenerative disease (ND) encounters lack of definitive treatment and challenges in …

Nanomedicine to overcome current Parkinson's treatment liabilities: A systematic review

GH Hawthorne, MP Bernuci, M Bortolanza… - Neurotoxicity …, 2016 - Springer
Nanoparticles might be produced and manipulated to present a large spectrum of
properties. The physicochemical features of the engineered nanomaterials confer to them …

[HTML][HTML] Importance of nanoparticles for the delivery of antiparkinsonian drugs

S Silva, AJ Almeida, N Vale - Pharmaceutics, 2021 - mdpi.com
Parkinson's disease (PD) affects around ten million people worldwide and is considered the
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …

[PDF][PDF] Emerging promise of nanoparticle-based treatment for Parkinson's disease

MM Rahman, KS Ferdous… - Biointerface Res. Appl …, 2020 - biointerfaceresearch.com
Neurodegenerative disorders are consequences of the deterioration of cells and tissues with
a mature undesirable way of life. The degenerative disease like Parkinson's disease (PD) …

Nanomaterials as novel agents for amelioration of Parkinson's disease

J Wu, X Cui, PC Ke, M Mortimer, X Wang, L Bao… - Nano Today, 2021 - Elsevier
Parkinson's disease (PD) is becoming prevalent with the increasingly ageing global
population. PD is a multi-factorial disease for which there is currently no cure but only …

Drug delivery systems for imaging and therapy of Parkinson's disease

M Silindir Gunay, A Yekta Ozer… - Current …, 2016 - ingentaconnect.com
Background: Although a variety of therapeutic approaches are available for the treatment of
Parkinson's disease, challenges limit effective therapy. Among these challenges are delivery …