Hypoxia increases heart rate (HR) in humans by sympathetic activation and vagal
withdrawal. However, in anaesthetized dogs hypoxia increases vagal activity and reduces …

We assessed the cardiovascular responses to systemic normocapnic hypoxia in five normal
subjects, five double lung transplant patients with lung denervation and intact hearts, and …

This study investigated whether changing sympathetic activity, acting via β-receptors, might
induce the progressive ventilatory changes observed in response to prolonged hypoxia. The …

Hyperoxia causes hemodynamic alterations. We hypothesized that cardiovascular and
autonomic control changes last beyond the end of hyperoxic period into normoxia. Ten …

This study examined the role of muscarinic parasympathetic mechanisms in generating the
progressive increases in ventilation (V̇E) and heart rate previously reported with 8 h …

The majority of the available works have studied distinct hypoxic responses of respiratory
and cardiovascular systems. This study examines how these systems interact while …

New Findings What is the central question of this research? Does increased ventilation
contribute to the increase in heart rate during transient exposure to hypoxia in humans …

METHODS During preliminary surgery, polyvinyl catheters were chronically implanted into
the left pulmonary artery and the left atrium directly and into the descending aorta (at the …

To examine whether the impacts of hypoxia on autonomic regulations involve the phasic
modulations as well as tonic controls of cardiovascular variables, heart rate, blood pressure …

Sustained and episodic hypoxic exposures lead, by two different mechanisms, to an
increase in ventilation after the exposure is terminated. Our aim was to investigate whether …