Mono-bronchodilator therapy versus dual bronchodilator therapy in symptomatic COPD patients: the Korea COPD Subgroup Study Team cohort

HJ Shin, TO Kim, YS Kwon - B39. COPD MANAGEMENT: FROM …, 2022 - atsjournals.org
Background: Although dual-bronchodilator therapy is superior to mono-bronchodilator
therapy in stable chronic obstructive pulmonary disease (COPD), the choice of mono …

Dual bronchodilation vs triple therapy in the “real-life” COPD DACCORD study

R Buhl, CP Criée, P Kardos… - … Journal of Chronic …, 2018 - Taylor & Francis
Background No observational studies have evaluated the “real-world” effectiveness of dual
bronchodilation comprising a long-acting β2-agonist plus a long-acting muscarinic …

Impact of switching from triple therapy to dual bronchodilation in COPD: the DACCORD 'real world'study

CF Vogelmeier, H Worth, R Buhl, CP Criée… - Respiratory …, 2022 - Springer
Introduction Chronic obstructive pulmonary disease (COPD) guidelines recommend
reserving triple therapy of inhaled corticosteroid (ICS), long-acting β2-agonist (LABA) and …

Impact of baseline COPD symptom severity on the benefit from dual versus mono-bronchodilators: an analysis of the EMAX randomised controlled trial

CF Vogelmeier, EM Kerwin… - Therapeutic …, 2020 - journals.sagepub.com
Rationale: Symptom relief is a key treatment goal in patients with chronic obstructive
pulmonary disease (COPD). However, there are limited data available on the response to …

Future concepts in bronchodilation for COPD: dual-versus monotherapy

D Singh, JF Donohue, IH Boucot… - European …, 2021 - Eur Respiratory Soc
Most patients with COPD are recommended to initiate maintenance therapy with a single
long-acting bronchodilator, such as a long-acting muscarinic antagonist or long-acting β2 …

Late Breaking Abstract-Comparative real world effectiveness of triple therapy versus dual bronchodilation in frequently exacerbating patients with COPD

J Voorham, M Kerkhof, M Scuri, S Vezzoli, I Valente… - 2018 - Eur Respiratory Soc
Background: Randomized controlled clinical trials support the efficacy of triple therapy (ICS+
LAMA+ LABA or TT) as compared to dual bronchodilation (LAMA+ LABA or DB) …

Dual versus monotherapy with bronchodilators in GOLD group B COPD patients according to baseline FEV1 level: a patient-level pooled analysis of phase-3 …

J Kang, JS Lee, SW Lee, JB Lee, YM Oh - Respiratory Research, 2021 - Springer
Background Which patients should receive dual therapy as initial treatment for chronic
obstructive pulmonary disease (COPD) is only loosely defined. We evaluated if a lower …

Comparative effectiveness of triple therapy versus dual bronchodilation in COPD

J Voorham, M Corradi, A Papi… - ERJ Open …, 2019 - Eur Respiratory Soc
This real-world study compared the effectiveness of triple therapy (TT; long-acting
muscarinic antagonists (LAMAs)/long-acting inhaled β-agonists (LABAs)/inhaled …

Triple therapy for the management of COPD: a review

K Gaebel, RA McIvor, F Xie, G Blackhouse… - COPD: Journal of …, 2011 - Taylor & Francis
Triple therapy for COPD consists of a long-acting anti-cholinergic bronchodilator, a long-
acting beta-agonist bronchodilator, and an inhaled corticosteroid. Guidelines from the …

Comparative efficacy of combination bronchodilator therapies in COPD: a network meta-analysis

EL Huisman, SM Cockle, AS Ismaila… - … Journal of Chronic …, 2015 - Taylor & Francis
Background Several new fixed-dose combination bronchodilators have been recently
launched, and assessing their efficacy relative to each other, and with open dual …