[HTML][HTML] Bacterial outer membrane vesicles as a candidate tumor vaccine platform

S Wang, J Guo, Y Bai, C Sun, Y Wu, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer represents a serious concern for human life and health. Due to drug resistance and
the easy metastasis of tumors, there is urgent need to develop new cancer treatment …

[HTML][HTML] Bacterial outer membrane vesicle-based cancer nanovaccines

X Gao, Q Feng, J Wang, X Zhao - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in
recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune …

Bacterial outer membrane vesicles as a versatile tool in vaccine research and the fight against antimicrobial resistance

Z Zhu, F Antenucci, KR Villumsen, AM Bojesen - MBio, 2021 - Am Soc Microbiol
Gram-negative bacteria include a number of pathogens that cause disease in humans and
animals. Although antibiotics are still effective in treating a considerable range of infections …

[HTML][HTML] Synergistic protective activity of tumor-specific epitopes engineered in bacterial outer membrane vesicles

A Grandi, M Tomasi, I Zanella, L Ganfini… - Frontiers in …, 2017 - frontiersin.org
Introduction Bacterial outer membrane vesicles (OMVs) are naturally produced by all Gram-
negative bacteria and, thanks to their plasticity and unique adjuvanticity, are emerging as an …

[HTML][HTML] Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based

W Cai, DK Kesavan, J Wan, MH Abdelaziz, Z Su… - Diagnostic pathology, 2018 - Springer
Abstract Both Gram-Positive and Gram-Negative bacteria can secrete outer membrane
vesicles (OMVs) in their growth and metabolism process. Originally, OMVs were considered …

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy

KS Park, K Svennerholm, R Crescitelli… - Journal of …, 2021 - Wiley Online Library
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer
vaccine platform for efficiently provoking immune responses. However, OMV induce severe …

[HTML][HTML] The therapeutic benefit of bacterial membrane vesicles

NJ Bitto, M Kaparakis-Liaskos - International journal of molecular …, 2017 - mdpi.com
The therapeutic potential of extracellular vesicles from eukaryotes has gained strong interest
in recent years. However, research into the therapeutic application of their bacterial …

[HTML][HTML] Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response

OY Kim, HT Park, NTH Dinh, SJ Choi, J Lee… - Nature …, 2017 - nature.com
Gram-negative bacteria actively secrete outer membrane vesicles, spherical nano-meter-
sized proteolipids enriched with outer membrane proteins, to the surroundings. Outer …

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy

Q Long, P Zheng, X Zheng, W Li, L Hua, Z Yang… - Advanced drug delivery …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

M Li, H Zhou, C Yang, Y Wu, X Zhou, H Liu… - Journal of Controlled …, 2020 - Elsevier
Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …