Objectives To examine the association between the Life Simple 7 cardiovascular health
score at age 50 and incidence of dementia. Design Prospective cohort study. Setting Civil …

Background Very few studies have explored the patterns of cardiovascular health (CVH)
metrics in midlife and late life in relation to risk of dementia. We examined the associations …

abstract Objective: To investigate the distribution of cognitive function in elderly people and
to assess the impact of clinical manifestations of atherosclerotic disease on this distribution …

Objective: To examine the relation of midlife raised blood pressure and serum cholesterol
concentrations to Alzheimer's disease in later life. Design: Prospective, population based …

Introduction Midlife clustering of vascular risk factors has been associated with late‐life
dementia, but causal effects of individual biological and lifestyle factors remain largely …

Background Sex differences in major cardiovascular risk factors for incident (fatal or non-
fatal) all-cause dementia were assessed in the UK Biobank. The effects of these risk factors …

Objective To determine the impact of lifestyle factors on life expectancy lived with and
without Alzheimer's dementia. Design Prospective cohort study. Setting The Chicago Health …

Previous research shows that cardiovascular risk factors in mid-adulthood could increase
the risk of dementia later in life, but studies with very long follow-up are still scarce. We …

Objective: To estimate the prevalence of dementia and its subtypes in the general
population and examine the relation of the disease to education. Design: Population based …

Background Gender-specific risks for dementia and Alzheimer's disease (AD) starting in
midlife remain largely unknown. Methods Prospectively ascertained dementia/AD and cause …