[PDF][PDF] Pharmacogenomics: introduction and use in clinical practice

H Saunders, D Harris, RM Chirilă - Romanian Journal of Internal …, 2020 - sciendo.com
Pharmacogenomics describes the link between the genetic code and variations in drug
response or adverse effects. It is rapidly gaining in both interest and accessibility. The …

Bringing genomics to the bedside: a cost-effective pharmacogenomic test?

DL Veenstra - Pharmacogenetics and Genomics, 2004 - journals.lww.com
Pharmacogenomics has been slow to be implemented in clinical practice, particularly for
commonly administered, chronic medications. In many ways, this is not surprising …

Pharmacogenomics: historical perspective and current status

R Charlab, L Zhang - Pharmacogenomics: Methods and Protocols, 2013 - Springer
Pharmacogenomics and its predecessor pharmacogenetics study the contribution of genetic
factors to the interindividual variability in drug efficacy and safety. One of the major goals of …

Pharmacogenetics and pharmacogenomics

JK Hicks, HL McLeod - Genomic and Precision Medicine, 2017 - Elsevier
Pharmacogenomics is a growing field of research that links genetic variation with drug
effects to determine impact on pharmacology and clinical application. Relationships …

Challenges for the application of pharmacogenomics associated with the nomenclature of allelic variants

N Godoy Torso, PC JL Santos, P Moriel - Pharmacogenomics, 2023 - Future Medicine
Pharmacogenomics is focused on the identification of genetic variant markers that influence
an individual's drug response profile through alterations in pharmacokinetics or …

Pharmacogenomics in general practice:'The time has come'

TM Polasek, K Mina, G Suthers - Australian Journal of General …, 2019 - search.informit.org
Background: Patients respond to medications differently because of variations in the genes
that determine medication exposure and medication response. Objective: The aim of this …

[HTML][HTML] Pharmacogenomics: the right drug to the right person

TP Aneesh, S Sekhar, A Jose, L Chandran… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic
variation on drug response in patients by correlating gene expression or single-nucleotide …

A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing

Y Zhou, S Koutsilieri, E Eliasson… - Basic & Clinical …, 2022 - Wiley Online Library
Genetic factors have long been recognized as important determinants of interindividual
variability in drug efficacy and toxicity. However, despite the increasing number of …

Introduction to pharmacogenetics

JH McDermott, W Newman - Drug and Therapeutics Bulletin, 2023 - dtb.bmj.com
There is considerable interindividual variability in the effectiveness and safety of medicines.
Although the reasons for this are multifactorial, it is well recognised that genetic changes …

Pharmacogenetics and pharmacogenomics: a clinical reality

R Ferraldeschi, WG Newman - Annals of Clinical …, 2011 - journals.sagepub.com
Pharmacogenetics and pharmacogenomics strive to explain the interindividual variability in
response to drugs due to genetic variation. For certain drugs, genetic tests can reduce …