[PDF][PDF] Pharmacogenomics: introduction and use in clinical practice
H Saunders, D Harris, RM Chirilă - Romanian Journal of Internal …, 2020 - sciendo.com
Pharmacogenomics describes the link between the genetic code and variations in drug
response or adverse effects. It is rapidly gaining in both interest and accessibility. The …
response or adverse effects. It is rapidly gaining in both interest and accessibility. The …
Bringing genomics to the bedside: a cost-effective pharmacogenomic test?
DL Veenstra - Pharmacogenetics and Genomics, 2004 - journals.lww.com
Pharmacogenomics has been slow to be implemented in clinical practice, particularly for
commonly administered, chronic medications. In many ways, this is not surprising …
commonly administered, chronic medications. In many ways, this is not surprising …
Pharmacogenomics: historical perspective and current status
R Charlab, L Zhang - Pharmacogenomics: Methods and Protocols, 2013 - Springer
Pharmacogenomics and its predecessor pharmacogenetics study the contribution of genetic
factors to the interindividual variability in drug efficacy and safety. One of the major goals of …
factors to the interindividual variability in drug efficacy and safety. One of the major goals of …
Pharmacogenetics and pharmacogenomics
Pharmacogenomics is a growing field of research that links genetic variation with drug
effects to determine impact on pharmacology and clinical application. Relationships …
effects to determine impact on pharmacology and clinical application. Relationships …
Challenges for the application of pharmacogenomics associated with the nomenclature of allelic variants
N Godoy Torso, PC JL Santos, P Moriel - Pharmacogenomics, 2023 - Future Medicine
Pharmacogenomics is focused on the identification of genetic variant markers that influence
an individual's drug response profile through alterations in pharmacokinetics or …
an individual's drug response profile through alterations in pharmacokinetics or …
Pharmacogenomics in general practice:'The time has come'
TM Polasek, K Mina, G Suthers - Australian Journal of General …, 2019 - search.informit.org
Background: Patients respond to medications differently because of variations in the genes
that determine medication exposure and medication response. Objective: The aim of this …
that determine medication exposure and medication response. Objective: The aim of this …
[HTML][HTML] Pharmacogenomics: the right drug to the right person
Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic
variation on drug response in patients by correlating gene expression or single-nucleotide …
variation on drug response in patients by correlating gene expression or single-nucleotide …
A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing
Y Zhou, S Koutsilieri, E Eliasson… - Basic & Clinical …, 2022 - Wiley Online Library
Genetic factors have long been recognized as important determinants of interindividual
variability in drug efficacy and toxicity. However, despite the increasing number of …
variability in drug efficacy and toxicity. However, despite the increasing number of …
Introduction to pharmacogenetics
JH McDermott, W Newman - Drug and Therapeutics Bulletin, 2023 - dtb.bmj.com
There is considerable interindividual variability in the effectiveness and safety of medicines.
Although the reasons for this are multifactorial, it is well recognised that genetic changes …
Although the reasons for this are multifactorial, it is well recognised that genetic changes …
Pharmacogenetics and pharmacogenomics: a clinical reality
R Ferraldeschi, WG Newman - Annals of Clinical …, 2011 - journals.sagepub.com
Pharmacogenetics and pharmacogenomics strive to explain the interindividual variability in
response to drugs due to genetic variation. For certain drugs, genetic tests can reduce …
response to drugs due to genetic variation. For certain drugs, genetic tests can reduce …