MF59-adjuvanted versus non-adjuvanted influenza vaccines: integrated analysis from a large safety database

M Pellegrini, U Nicolay, K Lindert, N Groth… - Vaccine, 2009 - Elsevier
BACKGROUND: Adding adjuvants such as MF59® to influenza vaccines can enhance the
immune response. This analysis evaluated the safety profile of MF59-adjuvanted [(+) MF59] …

Safety of MF59-adjuvanted versus non-adjuvanted influenza vaccines in children and adolescents: an integrated analysis

S Black, G Della Cioppa, A Malfroot, P Nacci, U Nicolay… - Vaccine, 2010 - Elsevier
We reviewed the safety of MF59-adjuvanted versus non-adjuvanted influenza vaccines in
children and adolescents (aged 6 months–18 years) in an integrated analysis of all pediatric …

MF59-adjuvanted vaccine: a safe and useful tool to enhance and broaden protection against seasonal influenza viruses in subjects at risk

P Durando, G Icardi, F Ansaldi - Expert opinion on biological …, 2010 - Taylor & Francis
Importance of the field: Vaccination is universally considered as the most effective tool for
the prevention of influenza, which represents a significant burden, both from a health-care …

Superior immunogenicity of seasonal influenza vaccines containing full dose of MF59® adjuvant: Results from a dose-finding clinical trial in older adults

G Della Cioppa, U Nicolay, K Lindert… - Human vaccines & …, 2012 - Taylor & Francis
Background: MF59-adjuvanted influenza vaccines have superior immunogenicity in older
adults compared with non-adjuvanted vaccines. We assessed whether changing formulation …

[HTML][HTML] Comparative effectiveness of adjuvanted versus high-dose seasonal influenza vaccines for older adults: a systematic review and meta-analysis

A Domnich, C de Waure - International Journal of Infectious Diseases, 2022 - Elsevier
Objectives MF59-adjuvanted standard-dose and nonadjuvanted high-dose seasonal
influenza vaccines have been developed to protect the elderly at high risk of severe …

[HTML][HTML] Trial of 2009 influenza A (H1N1) monovalent MF59-adjuvanted vaccine

TW Clark, M Pareek, K Hoschler, H Dillon… - … England Journal of …, 2009 - Mass Medical Soc
Background The 2009 pandemic influenza A (H1N1) virus has emerged to cause the first
pandemic of the 21st century. Development of effective vaccines is a public health priority …

Effectiveness of the MF59‐adjuvanted trivalent or quadrivalent seasonal influenza vaccine among adults 65 years of age or older, a systematic review and meta …

BL Coleman, R Sanderson, MDM Haag… - Influenza and other …, 2021 - Wiley Online Library
Background Standard‐dose seasonal influenza vaccines often produce modest
immunogenic responses in adults≥ 65 years old. MF59 is intended to elicit a greater …

Comparison of the safety and immunogenicity of an MF59®-adjuvanted with a non-adjuvanted seasonal influenza vaccine in elderly subjects

SE Frey, MR Aplasca-De Los Reyes, H Reynales… - Vaccine, 2014 - Elsevier
Aim Adjuvanted influenza vaccines can overcome the poor antibody response of
conventional non-adjuvanted vaccines in the elderly. We evaluated the immunogenicity …

MF59® Adjuvanted Seasonal and Pandemic Influenza Vaccines

TF Tsai - Yakugaku Zasshi, 2011 - jstage.jst.go.jp
MF59-adjuvanted seasonal trivalent inactivated (ATIV) vaccine licensed since 1997 and
MF59-adjuvanted pandemic H1N1 vaccines have been distributed to approximately 80M …

MF59 adjuvant: the best insurance against influenza strain diversity

DT O'Hagan, R Rappuoli, E De Gregorio… - Expert review of …, 2011 - Taylor & Francis
MF59 is a well-established, safe and potent vaccine adjuvant that has been licensed for
more than 13 years for use in an influenza vaccine focused on elderly subjects (Fluad® …