Comprehensive audiometric analysis of hearing impairment and tinnitus after cisplatin-based chemotherapy in survivors of adult-onset cancer

RD Frisina, HE Wheeler, SD Fossa… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Cisplatin is widely used but highly ototoxic. Effects of cumulative cisplatin dose on
hearing loss have not been comprehensively evaluated in survivors of adult-onset cancer …

Risk factors for ototoxicity due to cisplatin

BW Blakley, AK Gupta, SF Myers… - … of Otolaryngology–Head …, 1994 - jamanetwork.com
Objective: To determine whether abnormalities in routine blood tests were associated with
increased susceptibility to hearing loss induced by cisplatin chemotherapy. Design: Cohort …

Relationship between cisplatin administration and the development of ototoxicity

JM Rademaker-Lakhai, M Crul, L Zuur… - Journal of clinical …, 2006 - ascopubs.org
Purpose To determine the auditory toxicity associated with dose-and schedule-intensive
cisplatin/gemcitabine chemotherapy in non–small-cell lung carcinoma patients. Patients and …

Cisplatin ototoxicity: the importance of baseline audiometry

JL Nagy, DJ Adelstein, CW Newman… - American journal of …, 1999 - journals.lww.com
The role and optimal use of audiometry in monitoring for cisplatin ototoxicity are
incompletely defined. Audiograms were obtained from 217 patients before treatment with …

Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer

C Bokemeyer, CC Berger, JT Hartmann… - British journal of …, 1998 - nature.com
This study evaluates the degree and relevance of persisting ototoxicity after cisplatin-based
standard-dose chemotherapy for testicular cancer, with emphasis on identification of …

Ototoxicity from cisplatin therapy in childhood cancer

PP Coradini, L Cigana, SGA Selistre… - Journal of pediatric …, 2007 - journals.lww.com
Cisplatin has been associated with hearing damage. It is usually irreversible, bilateral, and
characterized by high-frequency sensorineural hearing loss. This study was carried out to …

Relative contributions of radiation and cisplatin-based chemotherapy to sensorineural hearing loss in head-and-neck cancer patients

YJ Hitchcock, JD Tward, A Szabo, BG Bentz… - International Journal of …, 2009 - Elsevier
PURPOSE: To investigate the risk of sensorineural hearing loss (SNHL) in patients with
head-and-neck cancer and treated with radiation therapy (RT) or concomitant cisplatin …

Ototoxic impact of cisplatin in pediatric oncology patients

AL Berg, JB Spitzer, JH Garvin Jr - The Laryngoscope, 1999 - Wiley Online Library
Objective: To describe hearing changes in a group of 28 children (age range, 8‐180 mo)
undergoing protocol‐based cisplatin therapy. Methods: Conventional, play audiometry …

A review of cisplatin-associated ototoxicity

J Paken, CD Govender, M Pillay… - Seminars in …, 2019 - thieme-connect.com
Cisplatin, an effective antineoplastic drug used in the treatment of many cancers, has
ototoxic potential, thus placing cancer patients, receiving this treatment, at risk of hearing …

Practical grading system for evaluating cisplatin ototoxicity in children

KW Chang, N Chinosornvatana - Journal of Clinical Oncology, 2010 - ascopubs.org
Purpose We present a new ototoxicity grading system that has clearly defined and frequency-
specific audiometric criteria. The purpose of this study was to validate this grading system by …