Secretome of adipose-derived stem cells cultured in platelet lysate improves migration and viability of keratinocytes

M Hermann, A Peddi, A Gerhards, R Schmid… - International Journal of …, 2023 - mdpi.com
Chronic wounds depict a silent epidemic challenging medical professionals worldwide.
Regenerative medicine uses adipose-derived stem cells (ADSC) in promising new …

Adipose-derived stem cells accelerate diabetic wound healing through the induction of autocrine and paracrine effects

YR Kuo, CT Wang, JT Cheng, GS Kao… - Cell …, 2016 - journals.sagepub.com
Cell-based therapy is an attractive approach for the treatment of chronic nonhealing
wounds. This study investigated whether adipose-derived stem cells (ASCs) can accelerate …

[HTML][HTML] Adipose-derived stem cells protect skin flaps against ischemia/reperfusion injury via IL-6 expression

CM Pu, CW Liu, CJ Liang, YH Yen, SH Chen… - Journal of Investigative …, 2017 - Elsevier
Flap necrosis is the most frequent postoperative complication encountered in reconstructive
surgery. We elucidated whether adipose-derived stem cells (ADSCs) and their derivatives …

A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration

P Li, X Guo - Stem cell research & therapy, 2018 - Springer
As the most important barrier for the human body, the skin often suffers from acute and
chronic injuries, especially refractory wounds, which seriously affect the quality of life of …

ADSCs enhance VEGFR3-mediated lymphangiogenesis via METTL3-mediated VEGF-C m6A modification to improve wound healing of diabetic foot ulcers

J Zhou, T Wei, Z He - Molecular Medicine, 2021 - Springer
Background Adipose-derived mesenchymal stem cells (ADSCs) are an important focus in
regenerative medicine. However, the biological function of ADSCs in the wound repair of …

Autologous adipose-derived stem cell transplantation enhances healing of wound with exposed bone in a rat model

T Hamada, H Matsubara, Y Yoshida, S Ugaji, I Nomura… - Plos one, 2019 - journals.plos.org
Objectives Soft tissue wounds with exposed bone often require extended healing times and
can be associated with severe complications. We describe the ability of artificial dermis with …

IGF‐1 promotes angiogenesis in endothelial cells/adipose‐derived stem cells co‐culture system with activation of PI 3K/Akt signal pathway

S Lin, Q Zhang, X Shao, T Zhang, C Xue, S Shi… - Cell …, 2017 - Wiley Online Library
Objectives The aim of this study was to investigate the role of insulin‐like growth factor‐1
(IGF‐1) and crosstalk between endothelial cells (EC s) and adipose‐derived stem cells …

Multiple injections of autologous adipose-derived stem cells accelerate the burn wound healing process and promote blood vessel regeneration in a rat model

X Zhou, K Ning, B Ling, X Chen, H Cheng… - Stem Cells and …, 2019 - liebertpub.com
Stem cell-based therapies have the potential to heal burn wounds, but thus far have had
limited success in clinical practice. This study aimed to test and improve the therapeutic …

Effects of adipose-derived stem cells and their conditioned medium in a human ex vivo wound model

X Guo, C Schaudinn, U Blume-Peytavi, A Vogt… - Cells, 2022 - mdpi.com
Adult stem cells have been extensively investigated for tissue repair therapies. Adipose-
derived stem cells (ASCs) were shown to improve wound healing by promoting re …

Galectin‐1 from conditioned medium of three‐dimensional culture of adipose‐derived stem cells accelerates migration and proliferation of human keratinocytes and …

MH Kim, WH Wu, JH Choi, J Kim, JH Jun… - Wound Repair and …, 2018 - Wiley Online Library
Keratinocytes and fibroblasts cells play important roles in the skin‐wound healing process
and are the cell types activated by trauma. Activated cells participate in epithelialization …