Local delivery of adipose-derived stem cells via acellular dermal matrix as a scaffold: a new promising strategy to accelerate wound healing

C Nie, D Yang, SF Morris - Medical hypotheses, 2009 - Elsevier
Wounds, characterized by leading to a loss of integrity of the skin and a major cause of
morbidity and mortality, are common challenges encountered in plastic and reconstructive …

Human fibroblast growth factor-treated adipose-derived stem cells facilitate wound healing and revascularization in rats with streptozotocin-induced diabetes mellitus

SY Chang, JH Lee, SC Oh, MY Lee, NK Lim - Cells, 2023 - mdpi.com
Diabetes mellitus contributes to 15–25% of all chronic foot ulcers. Peripheral vascular
disease is a cause of ischemic ulcers and exacerbates diabetic foot disease. Cell-based …

Adipose-derived Mesenchymal Stem Cells are Ideal for the Cell-based Treatment of Refractory Wounds: Strong Potential for Angiogenesis

Y Cao, J Yan, Z Dong, J Wang, X Jiang, T Cui… - Stem Cell Reviews and …, 2024 - Springer
Abstract Although Mesenchymal Stem Cells (MSCs)-based therapy has been proposed as a
promising strategy for the treatment of chronic lower-extremity ulcers, their optimal sources …

Interleukin‐6 from Adipose‐Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion‐Treated Skin …

CM Pu, YC Chen, YC Chen, TL Lee… - Mediators of …, 2019 - Wiley Online Library
The most common postoperative complication after reconstructive surgery is flap necrosis.
Adipose‐derived stem cells (ADSCs) and their secretomes are reported to mediate skin …

Effects of adipose stem cell-conditioned medium on the migration of vascular endothelial cells, fibroblasts and keratinocytes Retraction in/10.3892/etm. 2016.3709

LI Hu, J Zhao, J Liu, N Gong… - Experimental and …, 2013 - spandidos-publications.com
Adipose stem cell‑conditioned medium (ASC‑CM) has been successfully used to treat
multiple types of tissue and organ defects, including skin wounds both in vitro and in vivo …

LPS-pretreatment adipose-derived mesenchymal stromal cells promote wound healing in diabetic rats by improving angiogenesis

K Wang, Z Chen, L Jin, L Zhao, L Meng, F Kong, C He… - Injury, 2022 - Elsevier
Mesenchymal stem cells (MSCs) play a key role in wound healing, and the advantages of
pretreated MSCs in wound healing have previously been reported. In the present study, we …

Impact of hyperglycemia and low oxygen tension on adipose-derived stem cells compared with dermal fibroblasts and keratinocytes: importance for wound healing in …

A Lafosse, C Dufeys, C Beauloye, S Horman… - PLoS …, 2016 - journals.plos.org
Aim Adipose-derived stem cells (ASC) are currently proposed for wound healing in those
with type 2 diabetes mellitus (T2DM). Therefore, this study investigated the impact of …

Injection of stem cells derived from allogeneic adipose tissue, a new strategy for the treatment of diabetic wounds

R Izadi, SH Hejazi, S Bahramikia - Journal of Diabetes and its …, 2023 - Elsevier
A diabetic wound is one of the major complications of Diabetes mellitus. Considering the
impact of these wounds on the health and quality of life of diabetic patients, the need for a …

Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice

J Rodriguez, F Boucher, C Lequeux… - Stem Cell Research & …, 2015 - Springer
Background The use of stem cells from adipose tissue or adipose-derived stem cells (ASCs)
in regenerative medicine could be an interesting alternative to bone marrow stem cells …

Human platelet lysate-cultured adipose-derived stem cell sheets promote angiogenesis and accelerate wound healing via CCL5 modulation

YC Chen, EY Chuang, YK Tu, CL Hsu… - Stem Cell Research & …, 2024 - Springer
Background A rising population faces challenges with healing-impaired cutaneous wounds,
often leading to physical disabilities. Adipose-derived stem cells (ASCs), specifically in the …