The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory
responses both in response to and acting as danger signals. It has long been established …

During inflammation, functional changes occur in the vasculature, including extensive
endothelial cell mitotic activity and remodeling of capillaries. Interleukin‐1α.(IL‐1α) is a …

The angiogenic process involves several cell types and mediators, which interact to
establish a specific microenvironment suitable for the formation of new capillaries from pre …

Tumor angiogenesis is one of the hallmarks of tumor progression and is essential for
invasiveness and metastasis. Myeloid inflammatory cells, such as immature myeloid …

Angiogenesis is a vital biological process, and neovascularization is essential for the
development, wound repair, and perfusion of ischemic tissue. Neovascularization and …

IL-1β is a pleotropic cytokine that may mediate increased procoagulant activity and
permeability in endothelial tissue during inflammatory conditions. The procoagulant effects …

Reactive oxygen species, particularly superoxide, promote endothelial dysfunction and
alterations in vascular structure. It is increasingly recognized that inflammatory cytokines …

Interleukin (IL)-1 is an important mediator of inflammation and cardiovascular disease. Here,
we examined the role of IL-1 in arterial neointima formation. Carotid artery neointima was …

Angiogenesis is a critical process for growth of new capillary blood vessels from preexisting
capillaries and postcapillary venules, both in physiological and pathological conditions …

Vascular endothelial growth factor A (VEGF) is critical for vascular remodelling during tissue
repair subsequent to inflammation or injury, but under pathological conditions, VEGF …