Occurrence of Hepatoblastomas in Patients with Beckwith–Wiedemann Spectrum (BWSp)

SD Klein, M DeMarchis, RL Linn, SP MacFarland… - Cancers, 2023 - mdpi.com
Simple Summary Beckwith–Wiedemann syndrome (BWS) is an overgrowth and cancer
predisposition disorder that is associated with increased risk of hepatoblastoma (HB), a liver …

Phenotype, cancer risk, and surveillance in Beckwith–Wiedemann syndrome depending on molecular genetic subgroups

SM Maas, F Vansenne, DJM Kadouch… - American journal of …, 2016 - Wiley Online Library
Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

[PDF][PDF] Molecular networks of hepatoblastoma predisposition and oncogenesis in Beckwith‐Wiedemann syndrome

NS Sobel Naveh, EM Traxler, KA Duffy… - Hepatology …, 2022 - Wiley Online Library
Abstract Beckwith‐Wiedemann Syndrome (BWS) is the most common human overgrowth
disorder caused by structural and epigenetic changes to chromosome 11p15. Patients with …

Screening hepatoblastoma in Beckwith-Wiedemann syndrome: a complex issue

A Mussa, GB Ferrero - Journal of Pediatric Hematology/Oncology, 2015 - journals.lww.com
Trobaugh-Lotrario et al 1 are to be congratulated on their detailed review of cases of
Beckwith-Wiedemann Syndrome (BWS) with hepatoblastoma. We think that details …

Molecular subtypes and phenotypic expression of Beckwith–Wiedemann syndrome

WN Cooper, A Luharia, GA Evans, H Raza… - European journal of …, 2005 - nature.com
Abstract Beckwith–Wiedemann Syndrome (BWS) results from mutations or epigenetic
events involving imprinted genes at 11p15. 5. Most BWS cases are sporadic and uniparental …

Concurrent hepatoblastoma and Wilms tumor leading to diagnosis of Beckwith-Wiedemann syndrome

DM Wolfe, AW Carrion, MM Masukhani… - Journal of pediatric …, 2023 - journals.lww.com
Beckwith-Wiedemann syndrome (BWS) is an epigenetic overgrowth disorder and cancer
predisposition syndrome caused by imprinting defects of chromosome 11p15. 5-11p15. 4 …

The utility of alpha‐fetoprotein screening in Beckwith–Wiedemann syndrome

KA Duffy, MA Deardorff… - American Journal of …, 2017 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is one of the most common cancer predisposition
disorders. As a result, BWS patients receive tumor screening as part of their clinical …

[HTML][HTML] Genomic profiles of a hepatoblastoma from a patient with Beckwith-Wiedemann syndrome with uniparental disomy on chromosome 11p15 and germline …

SY Kim, SH Jung, MS Kim, MR Han, HC Park… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth disorder mainly
associated with altered genomic imprinting at chromosome 11p15. 5. Children with BWS …

Diagnosis of Beckwith–Wiedemann syndrome in children presenting with Wilms tumor

SP MacFarland, KA Duffy, TR Bhatti… - Pediatric blood & …, 2018 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is a genetic syndrome associated with overgrowth
and cancer predisposition, including predisposition to Wilms tumor (WT). Patients with BWS …

Cancer risk in Beckwith-Wiedemann syndrome: a systematic review and meta-analysis outlining a novel (Epi) genotype specific histotype targeted screening protocol

A Mussa, C Molinatto, G Baldassarre, E Riberi… - The Journal of …, 2016 - Elsevier
Objective To compare tumor risk in the 4 Beckwith-Wiedemann syndrome (BWS) molecular
subgroups: Imprinting Control Region 1 Gain of Methylation (ICR1-GoM), Imprinting Control …