(Epi) genotype–phenotype correlations in Beckwith–Wiedemann syndrome: a paradigm for genomic medicine

A Mussa, S Russo, L Larizza, A Riccio… - Clinical …, 2016 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is the commonest overgrowth cancer predisposition
disorder and represents a model for human imprinting dysregulation and tumorigenesis …

Diffuse infantile hepatic hemangiomas in a patient with Beckwith–Wiedemann syndrome: A new association?

M Macchiaiolo, AH Markowich… - American Journal of …, 2020 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome, caused by alterations
in a cluster of imprinted genes located within the chromosome region 11p15. 5. Common …

Epigenotyping as a tool for the prediction of tumor risk and tumor type in patients with Beckwith-Wiedemann syndrome (BWS)

J Bliek, C Gicquel, S Maas, V Gaston, Y Le Bouc… - The Journal of …, 2004 - Elsevier
OBJECTIVES: Patients with Beckwith-Wiedemann syndrome (BWS) have a risk of 7.5% to
10% of developing childhood tumors, 60% of which are Wilms' tumors. Aberrant methylation …

Tumor screening in Beckwith–Wiedemann syndrome—To screen or not to screen?

JM Kalish, MA Deardorff - … Journal of Medical Genetics Part A, 2016 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is the most common imprinting disorder and
consequently, one of the most common cancer predisposition disorders. Over the past 20 …

Management of adrenal masses in patients with Beckwith–Wiedemann syndrome

SP MacFarland, S Mostoufi‐Moab… - Pediatric blood & …, 2017 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is a genetic overgrowth and cancer predisposition
syndrome, associated with both benign and malignant adrenal findings. Literature review …

Comparative genomic hybridization analysis of hepatoblastomas: additional evidence for a genetic link with Wilms tumor and rhabdomyosarcoma

M Steenman, G Tomlinson, A Westerveld… - Cytogenetics and cell …, 1999 - karger.com
We applied the technique of comparative genomic hybridization (CGH) to a series of 16
hepatoblastomas. Our goals were (1) to identify all quantitative chromosome abnormalities …

Characterization of the Beckwith‐Wiedemann spectrum: Diagnosis and management

KA Duffy, CM Cielo, JL Cohen… - American Journal of …, 2019 - Wiley Online Library
Beckwith‐Wiedemann syndrome (BWS) is the most common epigenetic overgrowth and
cancer predisposition disorder. Due to both varying molecular defects involving …

[HTML][HTML] Adrenal cortical neoplasm with uncertain malignant potential arising in the heterotopic adrenal cortex in the liver of a patient with Beckwith-Wiedemann …

EN Kim, DE Song, HM Yoon… - Journal of Pathology …, 2019 - synapse.koreamed.org
Abstract Patients with Beckwith-Wiedemann syndrome (BWS) are predisposed to
developing embryonal tumors, with hepatoblastoma being the most common type. Our …

Characteristics and outcome of children with Beckwith-Wiedemann syndrome and Wilms' tumor: a report from the National Wilms Tumor Study Group

MH Porteus, P Narkool, D Neuberg… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: Children with Beckwith-Wiedemann syndrome (BWS) are at increased risk for
developing Wilms' tumor (WT). We reviewed the National Wilms Tumor Study Group …

Expanded phenotype and cancer risk in patients with Beckwith–Wiedemann spectrum caused by CDKN1C variants

AM George, A Viswanathan, LG Best… - American Journal of … - Wiley Online Library
Abstract Beckwith–Wiedemann spectrum (BWSp) is caused by genetic and epigenetic
alterations on chromosome 11 that regulate cell growth and division. Considering the …