Concurrent hepatoblastoma and Wilms tumor leading to diagnosis of Beckwith-Wiedemann syndrome

DM Wolfe, AW Carrion, MM Masukhani… - Journal of pediatric …, 2023 - journals.lww.com
Beckwith-Wiedemann syndrome (BWS) is an epigenetic overgrowth disorder and cancer
predisposition syndrome caused by imprinting defects of chromosome 11p15. 5-11p15. 4 …

Simultaneous presentation of Wilms tumor and immature ovarian teratoma in Beckwith-Wiedemann syndrome

JC White, J Liu, A Nahar - Journal of pediatric hematology …, 2018 - journals.lww.com
Abstract The Beckwith-Wiedemann syndrome is a cancer predisposition syndrome
characterized by a predilection to embryonal tumor growth, especially Wilms tumor …

Screening hepatoblastoma in Beckwith-Wiedemann syndrome: a complex issue

A Mussa, GB Ferrero - Journal of Pediatric Hematology/Oncology, 2015 - journals.lww.com
Trobaugh-Lotrario et al 1 are to be congratulated on their detailed review of cases of
Beckwith-Wiedemann Syndrome (BWS) with hepatoblastoma. We think that details …

Molecular basis of Beckwith–Wiedemann syndrome spectrum with associated tumors and consequences for clinical practice

T Eggermann, ER Maher, CP Kratz, D Prawitt - Cancers, 2022 - mdpi.com
Simple Summary Beckwith–Wiedemann syndrome (BWS, OMIM 130650) is an inborn
overgrowth disorder caused by molecular alterations in chromosome 11p15. 5. These …

Diagnosis of Beckwith–Wiedemann syndrome in children presenting with Wilms tumor

SP MacFarland, KA Duffy, TR Bhatti… - Pediatric blood & …, 2018 - Wiley Online Library
Beckwith–Wiedemann syndrome (BWS) is a genetic syndrome associated with overgrowth
and cancer predisposition, including predisposition to Wilms tumor (WT). Patients with BWS …

Phenotype, cancer risk, and surveillance in Beckwith–Wiedemann syndrome depending on molecular genetic subgroups

SM Maas, F Vansenne, DJM Kadouch… - American journal of …, 2016 - Wiley Online Library
Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

Novel deletion in 11p15. 5 imprinting center region 1 in a patient with Beckwith–Wiedemann syndrome provides insight into distal enhancer regulation and …

N Bachmann, R Crazzolara, F Bohne… - Pediatric Blood & …, 2017 - Wiley Online Library
Abstract Background Beckwith–Wiedemann syndrome (BWS) is an early‐onset overgrowth
disorder with a high risk for embryonal tumors. It is mainly caused by dysregulation of …

Neonatal hepatoblastoma in a newborn with severe phenotype of Beckwith–Wiedemann syndrome

A Mussa, GB Ferrero, B Ceoloni, E Basso… - European journal of …, 2011 - Springer
Beckwith–Wiedemann syndrome is an overgrowth disorder characterized by neonatal
macrosomia, abdominal wall defects, macroglossia, renal anomalies, organomegaly …

Molecular biology of Beckwith‐Wiedemann syndrome

R Weksberg, JA Squire - … Oncology: The Official Journal of SIOP …, 1996 - Wiley Online Library
Beckwith‐Wiedemann syndrome (BWS) is an overgrowth syndrome associated with a
predisposition to embryonal tumors, most commonly Wilms'(WT). Overlapping clinical …

Beckwith-Wiedemann syndrome-associated hepatoblastoma: wnt signal activation occurs later in tumorigenesis in patients with 11p15. 5 uniparental disomy

R Fukuzawa, J Hata, Y Hayashi, H Ikeda… - Pediatric and …, 2003 - Springer
Beckwith-Wiedemann syndrome (BWS) patients with chromosome 11p15. 5 uniparental
isodisomy (UPD) have an increased risk for developing embryonal tumors. UPD in these …