The present report describes current concepts about the mechanism of liver cell injury
caused by host immune response against hepatitis C virus (HCV) infection in human beings …

HCV (hepatitis C virus) has a high propensity to persist and to cause chronic hepatitis C,
eventually leading to cirrhosis. Since HCV itself is not cytopathic, liver damage in chronic …

Natural immune responses, both cellular and humoral, are not capable of terminating HCV
infection in most patients. The aim of this study was to evaluate: a) the importance of the …

Hepatitis C virus (HCV) is a highly mutable, hepatotropic RNA virus that causes acute and
chronic hepatitis, affecting over 3% of world population [1–8]. HCV infection frequently …

The liver is a special lymphoid organ with its own defense mechanism and it is prone to
chronic viral and autoimmune diseases. All constituent liver cells are involved in immune …

Abstract Background/Aims: The pathogenesis of liver cell injury in chronic hepatitis C is
poorly understood. To test whether immune-mediated mechanisms might be involved in the …

Virus-specific cytotoxic T lymphocytes (CTLs) have been suggested to be responsible for the
liver injuries in patients with hepatitis C virus (HCV) infection. However, there has been no …

Among seven human hepatitis viruses (A to E, G and TT virus), hepatitis B (HBV) and C
(HCV) viruses are able to persist in the host for years and principally contribute to the …

Abstract Hepatitis C Virus (HCV) induces a chronic infection in 50%–80% of infected
individuals, which can lead to cirrhosis and hepatocellular carcinoma. The inefficiency of the …

Despite advances in the knowledge of the epidemiology and molecular virology of hepatitis
C virus (HCV), the mechanisms of hepatocellular injury in HCV infection are not completely …