Task-dependent effects of SKF83959 on operant behaviors associated with distinct changes of CaMKII signaling in striatal subareas
PP Liu, CC Chao, RM Liao - International Journal of …, 2021 - academic.oup.com
Background SKF83959, an atypical dopamine (DA) D1 receptor agonist, has been used to
test the functions of DA-related receptor complexes in vitro, but little is known about its …
test the functions of DA-related receptor complexes in vitro, but little is known about its …
Comparison of the discriminative-stimulus effects of SKF 38393 with those of other dopamine receptor agonists
RI Desai, P Terry, JL Katz - Behavioural pharmacology, 2003 - journals.lww.com
The dopamine D 1-like receptor agonists have traditionally been defined molecularly by
their efficacy in stimulating adenylyl cyclase. However, evidence correlating the …
their efficacy in stimulating adenylyl cyclase. However, evidence correlating the …
SKF 38393 alters the rate‐dependent D2‐mediated inhibition of nigrostriatal but not mesoaccumbens dopamine neurons
MD Kelland, AS Freeman, LA Chiodo - Synapse, 1988 - Wiley Online Library
Previous electrophysiological studies have failed to identify significant effects of the D1
dopamine (DA) agonist SKF 38393, either alone or in combination with the D2 agonist …
dopamine (DA) agonist SKF 38393, either alone or in combination with the D2 agonist …
Activation of calcium/calmodulin-dependent protein kinase IIα in the striatum by the heteromeric D1-D2 dopamine receptor complex
J Ng, AJ Rashid, CH So, BF O'Dowd, SR George - Neuroscience, 2010 - Elsevier
Synaptic plasticity in the striatum is a key mechanism that underlies processes such as
reward related incentive learning and behavioral habit formation resulting from drugs of …
reward related incentive learning and behavioral habit formation resulting from drugs of …
Evidence against dopamine D1/D2 receptor heteromers
AL Frederick, H Yano, P Trifilieff, HD Vishwasrao… - Molecular …, 2015 - nature.com
Hetero-oligomers of G-protein-coupled receptors have become the subject of intense
investigation, because their purported potential to manifest signaling and pharmacological …
investigation, because their purported potential to manifest signaling and pharmacological …
D1 receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test
Rationale Impaired attention/vigilance is putatively core to schizophrenia. The dopaminergic
D 1 receptor system has been reported as one of the most promising targets for improving …
D 1 receptor system has been reported as one of the most promising targets for improving …
[HTML][HTML] Characterization of PF-6142, a novel, non-catecholamine dopamine receptor D1 agonist, in murine and nonhuman primate models of dopaminergic activation
R Kozak, T Kiss, K Dlugolenski, DE Johnson… - Frontiers in …, 2020 - frontiersin.org
Selective activation of dopamine D1 receptors remains a promising pro-cognitive
therapeutic strategy awaiting robust clinical investigation. PF-6142 is a key example from a …
therapeutic strategy awaiting robust clinical investigation. PF-6142 is a key example from a …
Repeated treatments with the D1 dopamine receptor agonist SKF-38393 modulate cell viability via sustained ERK–Bad–Bax activation in dopaminergic neuronal cells
HJ Park, TT Zhao, KH Park, MK Lee - Behavioural Brain Research, 2019 - Elsevier
The D 1 dopamine receptor agonist, SKF-38393, induces cytotoxicity in striatal
dopaminergic neurons via an extracellular signal-regulated kinase (ERK) signaling …
dopaminergic neurons via an extracellular signal-regulated kinase (ERK) signaling …
Reward-potentiating effects of D-1 dopamine receptor agonist and AMPAR GluR1 antagonist in nucleus accumbens shell and their modulation by food restriction
KD Carr, S Cabeza de Vaca, Y Sun, LS Chau - Psychopharmacology, 2009 - Springer
Rationale Previous studies have suggested that chronic food restriction (FR) increases
sensitivity of a neural substrate for drug reward. The neuroanatomical site (s) of key …
sensitivity of a neural substrate for drug reward. The neuroanatomical site (s) of key …
SKF83959 exhibits biochemical agonism by stimulating [35S] GTPγS binding and phosphoinositide hydrolysis in rat and monkey brain
S Panchalingam, AS Undie - Neuropharmacology, 2001 - Elsevier
SKF83959, a benzazepine with high affinity for aminergic receptors, elicits behaviors such
as grooming and vacuous chewing that are characteristic of dopamine D1-like receptor …
as grooming and vacuous chewing that are characteristic of dopamine D1-like receptor …