The use of natural compounds as a strategy to counteract oxidative stress in animal models of diabetes mellitus
M Salazar-García, JC Corona - International Journal of Molecular …, 2021 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic disease characterised by insulin deficiency,
resulting in hyperglycaemia, a characteristic symptom of type 2 diabetes mellitus (DM2). DM …
resulting in hyperglycaemia, a characteristic symptom of type 2 diabetes mellitus (DM2). DM …
Mechanistic insights into diabetes mellitus and oxidative stress
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - ingentaconnect.com
Diabetes mellitus (DM) is a significant healthcare concern worldwide that affects more than
165 million individuals leading to cardiovascular disease, nephropathy, retinopathy, and …
165 million individuals leading to cardiovascular disease, nephropathy, retinopathy, and …
Reactive species and diabetes: counteracting oxidative stress to improve health
P Pérez-Matute, MA Zulet, JA Martínez - Current opinion in pharmacology, 2009 - Elsevier
Oxidative stress is at the very core of metabolism. Reactive species behave as true second
messengers that control important cellular functions. However, under pathological …
messengers that control important cellular functions. However, under pathological …
Development and discovery avenues in bioactive natural products for glycemic novel therapeutics
SR Naik, GR Kokil - Studies in natural products chemistry, 2013 - Elsevier
Bioactive natural products are an excellent source of novel therapeutics. The search for
bioactive molecules from nature continues to play a major role in developing new …
bioactive molecules from nature continues to play a major role in developing new …
Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model
M Novelli, V D'Aleo, R Lupi, M Paolini, A Soleti… - Pancreas, 2007 - journals.lww.com
Objectives: We have previously established a nonobese diabetes mouse model
characterized by moderate hyperglycemic levels, like those usually occurring in human type …
characterized by moderate hyperglycemic levels, like those usually occurring in human type …
Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review
JO Unuofin, SL Lebelo - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
Bioactive agent discovery from the natural compounds for the treatment of type 2 diabetes rat model
SC Yang, CY Hsu, WL Chou, JY Fang, SY Chuang - Molecules, 2020 - mdpi.com
Diabetes mellitus is a well-known chronic metabolic disease that poses a long-term threat to
human health and is characterized by a relative or absolute lack of insulin, resulting in …
human health and is characterized by a relative or absolute lack of insulin, resulting in …
[PDF][PDF] Oxidative stress and diabetes: an overview
K Sireesha, SP Rao - Asian J Pharm Clin Res, 2015 - academia.edu
Oxidative stress is well known to be involved in the pathogenesis of lifestyle related
diseases. Oxidative stress contributes to many pathological conditions including cancer …
diseases. Oxidative stress contributes to many pathological conditions including cancer …
Animal models for assessing the impact of natural products on the aetiology and metabolic pathophysiology of Type 2 diabetes
Type 2 diabetes mellitus is a complex and heterogeneous disorder which in its most
common manifestation arises from insulin resistance and later insulin insufficiency. Type 2 …
common manifestation arises from insulin resistance and later insulin insufficiency. Type 2 …
Role of dietary and endogenous antioxidants in diabetes
G Marrazzo*, I Barbagallo*, F Galvano… - Critical reviews in …, 2014 - Taylor & Francis
Diabetes affects different people of all ages, race, and sex. This is a condition characterized
by a state of chronic hyperglycaemia that leads to an increase of intracellular oxidative …
by a state of chronic hyperglycaemia that leads to an increase of intracellular oxidative …