Environmental toxins are harmful substances detrimental to humans. Constant exposure to
these fatal neurotoxins can cause various neurodegenerative disorders. Although …

Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by cardinal motor impairments, including akinesia and tremor, as well as by a …

Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …

Publisher Summary This chapter discusses the interplay between the laboratory and the
clinic in analyzing the biological bases of parkinsonism arid formulating a rational approach …

Neurological disorders in humans can be modeled in animals using standardized
procedures that recreate specific pathogenic events and their behavioral outcomes. The …

Experimental models of dopaminergic neurodegeneration play a critical role in our quest to
elucidate the cause of Parkinson's disease (PD). Despite the recent development of “genetic …

Parkinson's disease (PD) is a common neurodegenerative disease that appears essentially
as a sporadic condition. It results mainly from the death of dopaminergic neurons in the …

Animal models for Parkinson's disease (PD) are very useful in understanding the
pathogenesis of PD and screening for new therapeutic approaches. The present study …

Animal models have been invaluable to Parkinson's disease (PD) research. Of these,
neurotoxin models have historically been the most widely utilized. The goal of this chapter is …

Animal models are a very important approach to study the pathogenesis and therapeutic
intervention strategies of human diseases. Since many human disorders do not arise …