Traumatic spinal cord injury (SCI) results in motor, autonomic and sensory impairment, and
is a condition for which there are no established therapies that promote repair or …

Spinal cord injury (SCI) results in the development of detrimental autoantibodies against the
lesioned spinal cord. IgM immunoglobulin maintains homeostasis against IgG-autoantibody …

The immune system plays a critical and complex role in the pathobiology of spinal cord
injury (SCI), exerting both beneficial and detrimental effects. Increasing evidence suggests …

Background: Cervical spinal cord injury (cSCI) accounts for approximately 60% of traumatic
SCI cases. In thoracic models of SCI, over-reactive antibody mediated responses adversely …

Background and Objectives Spinal cord injury (SCI) disrupts the fine-balanced interaction
between the CNS and immune system and can cause maladaptive aberrant immune …

The immune system has evolved primarily to protect the body from invasion by micro-
organisms such as bacteria, viruses, and parasites, and to contribute to repair processes …

Spinal cord injury (SCI) results in long-term neurological and systemic consequences,
including antibody-mediated autoimmunity, which has been related to impaired functional …

Neuroimmunology is a scientific discipline that seeks to understand the importance of
communication between the nervous and immune systems in both health and disease …

Introduction Spinal cord injury (SCI) is caused by two related but mechanistically distinct
events: the primary injury to the spinal cord is caused by a mechanic trauma; the secondary …

Background Evidence suggests that the inflammatory events in the acute phase of spinal
cord injury (SCI) exacerbate the initial trauma to the cord leading to poor functional recovery …