GEP-NETS UPDATE: Genetics of neuroendocrine tumors
J Crona, B Skogseid - European journal of endocrinology, 2016 - academic.oup.com
Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms, arising from
neuroendocrine cells that are dispersed throughout the body. Around 20% of NETs occur in …
neuroendocrine cells that are dispersed throughout the body. Around 20% of NETs occur in …
[HTML][HTML] Clinical epigenetics of neuroendocrine tumors: the road ahead
Neuroendocrine tumors, or NETs, are cancer originating in neuroendocrine cells. They are
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …
[HTML][HTML] NETs: organ-related epigenetic derangements and potential clinical applications
M Cives, V Simone, FM Rizzo, F Silvestris - Oncotarget, 2016 - ncbi.nlm.nih.gov
High-throughput next-generation sequencing methods have recently provided a detailed
picture of the genetic landscape of neuroendocrine tumors (NETs), revealing recurrent …
picture of the genetic landscape of neuroendocrine tumors (NETs), revealing recurrent …
Multilayered heterogeneity as an intrinsic hallmark of neuroendocrine tumors
Neuroendocrine tumors (NETs) comprise a complex and highly heterogeneous group of
neoplasms that can arise all over the body, originating from neuroendocrine cells. NETs are …
neoplasms that can arise all over the body, originating from neuroendocrine cells. NETs are …
Genetic and epigenetic drivers of neuroendocrine tumours (NET)
A Di Domenico, T Wiedmer, I Marinoni… - Endocrine-related …, 2017 - erc.bioscientifica.com
Neuroendocrine tumours (NET) of the gastrointestinal tract and the lung are a rare and
heterogeneous group of tumours. The molecular characterization and the clinical …
heterogeneous group of tumours. The molecular characterization and the clinical …
The biological characterization of neuroendocrine tumors: the role of neuroendocrine markers
Neuroendocrine tumors (NET) may originate in different organs, from cells embriologically
different but expressing common phenotypic characteristics, such as: the immuno-re-activity …
different but expressing common phenotypic characteristics, such as: the immuno-re-activity …
Genomics of high-grade neuroendocrine neoplasms: well-differentiated neuroendocrine tumor with high-grade features (G3 NET) and neuroendocrine carcinomas …
S Uccella, S La Rosa, J Metovic, D Marchiori… - Endocrine …, 2021 - Springer
High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …
classification of which has recently been redefined. They now include both poorly …
The genetics of neuroendocrine tumors
K Öberg - Seminars in oncology, 2013 - Elsevier
Neuroendocrine tumors (NETs) present a wide spectrum of malignant diseases from rather
benign to very malignant variants. The majority of these tumors are sporadic, but there are …
benign to very malignant variants. The majority of these tumors are sporadic, but there are …
Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms
A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …
Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies
RM Ruggeri, E Benevento, F De Cicco… - Journal of …, 2023 - Springer
Purpose Neuroendocrine neoplasms can occur as part of inherited disorders, usually in the
form of well-differentiated, slow-growing tumors (NET). The main predisposing syndromes …
form of well-differentiated, slow-growing tumors (NET). The main predisposing syndromes …