[HTML][HTML] Role of HTLV-1 Tax and HBZ in the pathogenesis of HAM/TSP

Y Enose-Akahata, A Vellucci, S Jacobson - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to development of adult
T cell leukemia/lymphoma (ATL) or HTLV-1-associated myelopathy/tropical spastic …

HTLV-1 HBZ protein resides exclusively in the cytoplasm of infected cells in asymptomatic carriers and HAM/TSP patients

G Forlani, M Baratella, A Tedeschi, C Pique… - Frontiers in …, 2019 - frontiersin.org
Human T cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis …

[HTML][HTML] HTLV-1 HBZ viral protein: a key player in HTLV-1 mediated diseases

M Baratella, G Forlani, RS Accolla - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus that has
infected 10–15 million people worldwide. After a long latency, 3–5% of infected individuals …

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

N Araya, T Sato, H Ando, U Tomaru… - The Journal of …, 2014 - Am Soc Clin Investig
Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical …

M Saito, T Matsuzaki, Y Satou, J Yasunaga, K Saito… - Retrovirology, 2009 - Springer
Background Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper
factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to …

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

M Kannagi, A Hasegawa, Y Nagano, S Kimpara… - Retrovirology, 2019 - Springer
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL),
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other …

The roles of acquired and innate immunity in human T-cell leukemia virus type 1-mediated diseases

M Kannagi, A Hasegawa, A Takamori… - Frontiers in …, 2012 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-
1-associated myelopathy/tropical spastic paraparesis in small subsets of HTLV-1 carriers …

[HTML][HTML] Association between HTLV-1 genotypes and risk of HAM/TSP

M Saito - Frontiers in microbiology, 2019 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a neurological disorder presenting with spastic paraparesis …

HTLV-1-mediated epigenetic pathway to adult T-cell leukemia–lymphoma

M Yamagishi, D Fujikawa, T Watanabe… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1), the first reported human oncogenic retrovirus,
is the etiologic agent of highly aggressive, currently incurable diseases such as adult T-cell …

[HTML][HTML] HTLV-1 alters T cells for viral persistence and transmission

A Tanaka, M Matsuoka - Frontiers in microbiology, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a
causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory …