Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

M Yoshida - Annual review of immunology, 2001 - annualreviews.org
The human T cell leukemia virus-1 (HTLV-1) is a retrovirus that causes adult T cell leukemia
(ATL) and neurological disorder, the tropical spastic paraparesis (HAM/TSP). The …

Human T-Cell Leukemia Virus Type 1 Oncogenesis between Active Expression and Latency: A Possible Source for the Development of Therapeutic Targets

F Marino-Merlo, S Grelli, A Mastino, M Lai… - International Journal of …, 2023 - mdpi.com
The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …

The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6

S Legros, M Boxus, JS Gatot, C Van Lint, V Kruys… - Oncogene, 2011 - nature.com
Human T cell leukemia virus type-1 (HTLV-1) is the causative agent of two major diseases: a
rapidly fatal leukemia designated adult T-cell leukemia and a neurological degenerative …

HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma

BJY Tan, K Sugata, O Reda, M Matsuo… - The Journal of …, 2021 - Am Soc Clin Investig
Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …

Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8+ T cells, and disease severity in HTLV-1–associated …

Y Yamano, M Nagai, M Brennan… - Blood, The Journal …, 2002 - ashpublications.org
To investigate the role of viral expression in individuals infected with human T-cell
lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase …

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

H Tarokhian, H Rahimi, A Mosavat, A Shirdel… - BMC cancer, 2018 - Springer
Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of
HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load …

A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation

A Lavorgna, M Matsuoka, EW Harhaj - PLoS pathogens, 2014 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult
T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1 associated …

HTLV-1 infection and pathogenesis: new insights from cellular and animal models

G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …

HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ

CZ Giam, OJ Semmes - Viruses, 2016 - mdpi.com
HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …

Molecular determinants of human T-lymphotropic virus type 1 transmission and spread

MD Lairmore, R Anupam, N Bowden, R Haines… - Viruses, 2011 - mdpi.com
Human T-lymphotrophic virus type-1 (HTLV-1) infects approximately 15 to 20 million people
worldwide, with endemic areas in Japan, the Caribbean, and Africa. The virus is spread …