Human T-cell leukemia viruses type 1 (HTLV-1) and type 2 (HTLV-2) share a common
genome organization and expression strategy but have distinct pathological properties …

We investigated the mechanism of lymphocyte infiltration into tissues infected with human T-
cell leukemia virus type 1 (HTLV-1). The cytokine SDF-1/PBSF is a highly efficient …

Background HTLV-1 causes proliferation of clonal populations of infected T cells in vivo,
each clone defined by a unique proviral integration site in the host genome. The proviral …

Human T cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be identified as a
causative agent of a cancer in humans. In addition to cancer, adult T-cell leukemia (ATL) …

Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …

Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T cells and induces proliferation
of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some …

Human T-cell leukemia virus type 1 (HTLV-1) is a complex human delta retrovirus that
infects an estimated 10–20 million people worldwide (Gessain and Cassar 2012). HTLV-1 …

The risk of developing adult T-cell leukemia/lymphoma (ATLL) in individuals infected with
human T-cell lymphotropic virus 1 (HTLV-1) is about 3–5%. The mechanisms by which the …

Background Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very
poor prognosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV …

Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1). ATL cells possess a CD4+ CD25+ phenotype, similar to that …