Introduction Relapsing-remitting multiple sclerosis (RRMS) is a chronic, immune-mediated
neurodegenerative disease with a highly heterogeneous disease course. Conventional MRI …

Introduction Quantitative microstructural MRI, such as myelin-sensitive magnetisation
transfer ratio (MTR) or saturation (MTsat), axon-sensitive water diffusion Neurite Orientation …

The purpose of this study was to correlate magnetic resonance imaging (MRI)-based lesion
load assessment with clinical disability in early relapsing remitting multiple sclerosis …

Purpose To investigate magnetization transfer ratio (MTR), T1 relaxation time, and proton
density (PD) as indicators of gray matter damage in relapsing‐remitting multiple sclerosis …

Myelin-sensitive MRI such as magnetisation transfer imaging has been widely used in the
clinical context of multiple sclerosis. The influence of methodology and differences in …

The clinical course of multiple sclerosis (MS) is highly variable ranging from benign to
aggressive, and is difficult to predict. Since magnetization transfer (MT) imaging can detect …

Background: Progression rates in primary progressive multiple sclerosis (PPMS) vary widely
and brain magnetisation transfer imaging (MTI) has potential as an early prognostic …

Abnormalities within normal–appearing grey and white matter (NAGM and NAWM) occur
early in the clinical course of multiple sclerosis (MS) and can be detected in–vivo using the …

Magnetic resonance imaging (MRI) has played a central role in the diagnosis and
management of multiple sclerosis (MS). In addition, MRI metrics have become key …

Background: In multiple sclerosis (MS), demyelination and neuro-axonal loss occur in the
brain grey matter (GM). We used magnetic resonance imaging (MRI) measures of GM …