Context There is growing evidence that major depressive disorder (MDD) might be
overdiagnosed at the expense of bipolar disorder (BPD). Objectives To identify a subgroup …

Manic and mixed episodes can be challenging to treat despite published guidelines and
algorithms. An alternative iterative approach that offers evidence-based treatment options at …

The Japanese Society of Mood Disorders (JSMD) published treatment guidelines of bipolar
disorder in 2011. The present guidelines incorporating new findings were developed to …

In recent years, combinations of pharmacological treatments have become common for the
treatment of bipolar disorder type I (BP I); however, this practice is usually not evidence …

Objectives In this study, we investigated and organized the maintenance-treatment
strategies for Bipolar I and II disorders outlined in The Korean Medication Algorithm Project …

IntroductionMixed features refers to the presence of high and low symptoms occurring at the
same time, or as part of a single episode, in people experiencing an episode of mania or …

Objective: Mixed episodes comprise up to 40% of acute bipolar admissions. They are
difficult‐to‐treat, complex clinical pictures. This review provides an overview of the available …

Background Due to complex clinical symptoms, bipolar Ⅰ disorder (BP-Ⅰ) is easily
misdiagnosed or underdiagnosed, and difficult to treat, and has relatively high recurrence …

When I got into psychiatry in 2001 after working as a physician for 13 years, my image of a
depressed patient was that of an exhausted, sad, and quiet person, which probably …

Bipolar disorder (BD) is associated with poor psychosocial functioning (eg, high divorce
rates; erratic work performance), significant medical and psychiatric comorbidities (eg …