pH-driven targeting nanoprobe with dual-responsive drug release for persistent luminescence imaging and chemotherapy of tumor

HJ Zhang, X Zhao, LJ Chen, CX Yang… - Analytical …, 2019 - ACS Publications
Multifunctional nanoprobes with both imaging and drug delivery capabilities represent an
emerging approach to the diagnosis and treatment of tumor. However, poor accumulation in …

Biomimetic persistent luminescent nanoplatform for autofluorescence-free metastasis tracking and chemophotodynamic therapy

YJ Li, CX Yang, XP Yan - Analytical chemistry, 2018 - ACS Publications
Metastasis is the main cause of death in people with cancer. Early diagnosis and targeted
therapy for metastasis is crucial for the survival of the cancer patients. However, metastasis …

Liposome-coated persistent luminescence nanoparticles as luminescence trackable drug carrier for chemotherapy

LJ Chen, CX Yang, XP Yan - Analytical Chemistry, 2017 - ACS Publications
Near-infrared persistent luminescence nanoparticles (NIR-PLNPs) are promising imaging
agents due to deep tissue penetration, high signal-to-noise ratio, and repeatedly charging …

Dendrimer grafted persistent luminescent nanoplatform for aptamer guided tumor imaging and acid-responsive drug delivery

HJ Zhang, X Zhao, LJ Chen, CX Yang, XP Yan - Talanta, 2020 - Elsevier
Theranostic nano-drug delivery systems are promising candidates for early diagnosis and
treatment of tumors. However, it is a great challenge to achieve accurate intracellular …

Persistent luminescent nanoparticles containing hydrogels for targeted, sustained, and autofluorescence-free tumor metastasis imaging

H Zhao, C Liu, Z Gu, L Dong, F Li, C Yao, D Yang - Nano Letters, 2019 - ACS Publications
Metastasis is the primary cause of cancer morbidity and mortality. To obtain an effective
diagnosis and treatment, precise imaging of tumor metastasis is required. Here we prepared …

Dual-emissive persistent luminescence nanoparticle-based charge-reversible intelligent nanoprobe for persistent luminescence-ratio bioimaging along with chemo …

JL Liu, X Zhao, LJ Chen, LM Pan, XP Yan - Analytical Chemistry, 2021 - ACS Publications
Persistent luminescence nanoparticles (PLNPs) hold great promise for bioimaging owing to
no demand for in situ excitation and negligible tissue autofluorescence interference …

Energy recruitment via lanthanide-chelate to boost the persistent luminescence of nanophosphor for contrast-enhanced tumor navigation

M Sun, C Yin, Z Yan, ZJ Wei, Z Zhang, W Wang… - Chemical Engineering …, 2023 - Elsevier
Abstract Persistent luminescence (PersL) nanoparticles (PLNPs) with excitation-afterglow
emission separation character, have brought luciferous prospect for ultrasensitive optical …

Engineering persistent luminescence nanoparticles for biological applications: from biosensing/bioimaging to theranostics

SK Sun, HF Wang, XP Yan - Accounts of chemical research, 2018 - ACS Publications
Conspectus Persistent luminescence nanoparticles (PLNPs) are unique optical materials
emitting long-lasting luminescence after ceasing excitation. Such a unique optical feature …

A multifunctional persistent luminescent nanoprobe for imaging guided dual-stimulus responsive and triple-synergistic therapy of drug resistant tumor cells

FX Su, X Zhao, C Dai, YJ Li, CX Yang… - Chemical …, 2019 - pubs.rsc.org
We report the design and fabrication of a multifunctional persistent luminescent nanoprobe
for imaging guided dual-stimulus responsive and triple-synergistic therapy of drug resistant …

Design and engineering of hypoxia and acidic pH dual‐stimuli‐responsive intelligent fluorescent nanoprobe for precise tumor imaging

S Chen, M Chen, J Yang, X Zeng, Y Zhou, S Yang… - Small, 2021 - Wiley Online Library
Stimulus‐responsive fluorescence imaging modality shows great promise for detection of
tumor due to the advantages of high sensitivity, simplicity and noninvasiveness. However …