Influence of periodontal pathogens on induction of epithelial-mesenchymal transition (EMT) in oral keratinocytes

SS Shoker - 2022 - etheses.bham.ac.uk
Epithelial-mesenchymal transition (EMT) is a process where epithelial cells gain migratory
and invasive properties and is associated with dissolution of epithelial integrity. Inflammatory …

Potential involvement of epithelial-mesenchymal transition in the pathogenesis of periodontitis

AA Abdulkareem - 2017 - etheses.bham.ac.uk
Epithelial-mesenchymal transition is reportedly important in loss of epithelial integrity and
cell migration in inflammatory/infectious diseases and cancer. Since Gram negative …

Potential role of periodontal pathogens in compromising epithelial barrier function by inducing epithelial‐mesenchymal transition

AA Abdulkareem, RM Shelton, G Landini… - Journal of …, 2018 - Wiley Online Library
Background and Objective Epithelial‐mesenchymal transition (EMT) is a process by which
epithelial cells acquire a mesenchymal‐like phenotype and this may be induced by …

Periodontal pathogens promote epithelial-mesenchymal transition in oral squamous carcinoma cells in vitro

AA Abdulkareem, RM Shelton, G Landini… - Cell adhesion & …, 2018 - Taylor & Francis
Epithelial-mesenchymal transition (EMT) is potentially involved in increasing metastasis of
oral squamous cell carcinoma (OSCC). Periodontal pathogens are well-known for their …

Antibacterial activity of curcumin against periodontopathic bacteria

S Izui, S Sekine, K Maeda, M Kuboniwa… - Journal of …, 2016 - Wiley Online Library
Background: Curcumin is a polyphenol extracted from root of turmeric and known to possess
multifunctional properties, including antibacterial activity. Although previous studies have …

Human primary epithelial cells acquire an epithelial-mesenchymal-transition phenotype during long-term infection by the oral opportunistic pathogen, Porphyromonas …

J Lee, JAS Roberts, KR Atanasova… - Frontiers in cellular …, 2017 - frontiersin.org
Porphyromonas gingivalis is a host-adapted oral pathogen associated with chronic
periodontitis that successfully survives and persists in the oral epithelium. Recent studies …

Protective effect and related mechanisms of curcumin in rat experimental periodontitis

CJ Xiao, XJ Yu, JL Xie, S Liu, S Li - Head & face medicine, 2018 - Springer
Background Curcumin exhibits anti-inflammatory effects and has been suggested as a
treatment for inflammatory diseases. The aim of this study was to investigate the effects of …

[HTML][HTML] Epithelial–mesenchymal transition in gingival tissues from chronic periodontitis patients: A case–control study

KW Wadie, MH Bashir, MMS Abbass - Dental and medical …, 2021 - dmp.umw.edu.pl
Background. It has been proposed that epithelial–mesenchymal transition (EMT) is
responsible for the pathogenesis of several diseases. However, the relationship between …

Curcumin inhibits the expression of proinflammatory mediators and MMP-9 in gingival epithelial cells stimulated for a prolonged period with lipopolysaccharides …

S Toraya, O Uehara, D Hiraki, F Harada, P Neopane… - Odontology, 2020 - Springer
Curcumin, a yellow phytochemical found in the rhizomes of Curcuma longa, has various
biological effects, including anti-oxidant and anti-inflammatory activities. In the present study …

[HTML][HTML] Pathogenesis of periodontitis–A potential role for epithelial-mesenchymal transition

SS Saliem, SY Bede, PR Cooper… - … Dental Science Review, 2022 - Elsevier
Epithelial mesenchymal transition (EMT) is a process comprising cellular and molecular
events which result in cells shifting from an epithelial to a mesenchymal phenotype …