Natural killer cells in myeloid malignancies: immune surveillance, NK cell dysfunction, and pharmacological opportunities to bolster the endogenous NK cells
M Carlsten, M Järås - Frontiers in immunology, 2019 - frontiersin.org
Natural killer (NK) cells are large granular lymphocytes involved in our defense against
certain virus-infected and malignant cells. In contrast to T cells, NK cells elicit rapid anti …
certain virus-infected and malignant cells. In contrast to T cells, NK cells elicit rapid anti …
Natural killer cells: a review of biology, therapeutic potential and challenges in treatment of solid tumors
K Choucair, JR Duff, CS Cassidy, MT Albrethsen… - Future …, 2019 - Taylor & Francis
Natural killer (NK) cells lead immune surveillance against cancer and early elimination of
small tumors. Owing to their ability to engage tumor targets without the need of specific …
small tumors. Owing to their ability to engage tumor targets without the need of specific …
NK cells in the treatment of hematological malignancies
AP Gonzalez-Rodriguez, M Villa-Álvarez… - Journal of clinical …, 2019 - mdpi.com
Natural killer (NK) cells have the innate ability to kill cancer cells, however, tumor cells may
acquire the capability of evading the immune response, thereby leading to malignancies …
acquire the capability of evading the immune response, thereby leading to malignancies …
Natural killer cells: a promising immunotherapy for cancer
J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy
NK Wolf, DU Kissiov, DH Raulet - Nature Reviews Immunology, 2023 - nature.com
Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …
Natural killer cells: the linchpin for successful cancer immunotherapy
KA Shaver, TJ Croom-Perez, AJ Copik - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that
works by augmenting the body's own immune system. While various immune stimulation …
works by augmenting the body's own immune system. While various immune stimulation …
Natural killer cells: diverse functions in tumor immunity and defects in pre-neoplastic and neoplastic stages of tumorigenesis
Natural killer (NK) cells are the key immune effectors with the ability to mediate selection and
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …
Targeting natural killer cells in solid tumors
G Habif, A Crinier, P André, E Vivier… - Cellular & molecular …, 2019 - nature.com
Natural killer (NK) cells are innate lymphoid cells endowed with cytolytic activity and a
capacity to secrete cytokines and chemokines. Several lines of evidence suggest that NK …
capacity to secrete cytokines and chemokines. Several lines of evidence suggest that NK …
Human natural killer cell development and biology
SS Farag, MA Caligiuri - Blood reviews, 2006 - Elsevier
Natural killer cells are important innate immune effector cells with potentially broad
applications in the treatment of human malignancy due to their ability to lyse neoplastic cells …
applications in the treatment of human malignancy due to their ability to lyse neoplastic cells …
Therapeutic potential and challenges of natural killer cells in treatment of solid tumors
A Gras Navarro, AT Björklund, M Chekenya - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are innate lymphoid cells that hold tremendous potential for effective
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …